Buy Aethoxysklerol solution for injection 30 mg ml ampoules 2 ml 5 pcs

Aethoxysklerol solution for injection 30 mg ml ampoules 2 ml 5 pcs

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Active ingredients

Lauromacrogol 400

Release form

Solution

Composition

Active ingredient: Polidocanol Active ingredient concentration (mg): 30

Pharmacological effect

Sclerosing agent, non-ionic surfactant.

Pharmacokinetics

Distribution volume - 24.5 l, plasma protein binding - 64%, T1 / 2 - 4 h. Total Cl - 11.7 l / h, renal - 2.43 l / h, biliary - 3.14 l / h . With repeated injections does not accumulate.

Indications

For sclerosis of varicose veins of the limbs, esophagus, stomach, as well as hemorrhoids, peripheral and central veins telangiectasias.

Contraindications

Shock, endocarditis, myocarditis, chronic heart failure in the decompensation stage, acute infectious and inflammatory diseases accompanied by fever (including local), bronchial asthma, pulmonary diseases in the acute phase; diabetes mellitus in the phase of decompensation, diabetic microangiopathy; I trimester and after 36 weeks of pregnancy, with the exception of acute bleeding; hypersensitivity to the active substance. For sclerosis of varicose veins of the lower extremities: acute thrombosis of the superficial and deep veins, thrombophlebitis of the deep veins, occlusion of arteries of the 3rd and 4th degree. Not used in bedridden patients.

Precautionary measures

You can not enter in / a. When used in the ankle and ankle area, small amounts of 0.5% solution are recommended.

Use during pregnancy and lactation

It is contraindicated for use in the first trimester and after 36 weeks of pregnancy (with the exception of acute bleeding).

Dosage and administration

Individual, depending on indications and the applied dosage form.

Side effects

Systemic reactions: fever, exudative pleurisy are possible; rarely, skin rash; very rarely - collapse, dizziness, difficulty breathing and chest tightness, nausea, visual disturbances, local sensitivity disorders, metallic taste, anaphylactic shock. Local reactions: depending on the injection site, esophageal necrosis and ulceration may develop, dysphagia, esophageal stenosis, very rarely - esophageal perforation; hyperpigmentation, periphlebitis, thrombophlebitis, tissue necrosis (especially with paravasal administration); with sclerosis of hemorrhoids, transient pains are possible during and after the injection, very rarely, pain in the prostate gland, as well as transient erection disorders.

Interaction with other drugs

Enhances the arrhythmogenic effect of general anesthetics.

special instructions

Do not allow in / a introduction. The introduction of sclerosing agents into the veins of the facial part of the skull is possible only under strict indications. With extreme caution, it is used for varicose veins of the lower extremities in occlusion of arteries of the 2nd degree, as well as in elderly patients with limited ability to move and severe general condition. use with drugs for anesthesia there is a risk of arrhythmogenic action.

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