Exported powder for preparation of oral solution 10 g 20 pcs.
Condition: New product
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Active ingredients
Lactitol
Release form
Powder
Composition
1 sachet contains: Active substance: lactitol monohydrate 10 g.
Pharmacological effect
A laxative drug. In the large intestine, lactitol is broken down by the action of the intestinal flora into low molecular weight organic acids, which leads to an increase in osmotic pressure in the large intestine, an increase in the amount of feces, softening, relief of bowel movements and normalization of the bowels. The laxative effect usually occurs within 24 hours after the use of the drug (the delay is due to the passage of the drug through the gastrointestinal tract). At the beginning of the course of treatment, a laxative effect of the drug may be delayed; the effect may occur on the second or third day of its use. In patients with hepatic encephalopathy or hepatic coma (or precoma), the effect is achieved due to the migration of ammonia from the blood into the large intestine (due to a decrease in PH, osmotic pressure in the intestinal lumen), removal of retained ammonium ions and other nitrogen-containing toxic substances from the colon. Lactitol suppresses proteolytic bacteria and increases the amount of acido yl bacteria.
Pharmacokinetics
Lactitol carries out its effect only in the large intestine, where it completely enters after ingestion. It is absorbed in minimal quantities in unchanged form (no more than 0.5-2% of the accepted dose).
Indications
Constipation; the need for stool regulation for medical purposes (intestinal cleansing in preparation for endoscopic and x-ray examinations, surgery on the rectum, anal sphincter and the area adjacent to it); intestinal dysbacteriosis; hepatic encephalopathy, hepatic coma and precoma, hyperammonemia.
Contraindications
Galactosemia, intestinal obstruction, suspicion of organic lesions of the gastrointestinal tract, abdominal pain and rectal bleeding of unknown origin, individual intolerance to lactitol.
Dosage and administration
The drug is administered orally during the meal, mixing with various drinks (water, tea, coffee, juices) or liquid food. In case of constipation and dysbacteriosis, the drug should be taken once, the entire daily dose at once,for 1 reception. Children aged 1-6 years appoint 2.5-5 g (1 / 2-1 teaspoon of powder) / day; children aged 6-12 years - 5-10 g (1-2 teaspoons of powder) / day; children aged 12-16 years - 10-20 g (2-4 teaspoons of powder) / day; adults - 20 g (4 teaspoons of powder) / day. The drug should cause stool 1 time / day; after the onset of a stable laxative effect within a few days of use of the drug, its dose can be reduced. In some cases, to obtain the desired effect, half of the recommended daily dose is sufficient. The minimum course of therapy, after which you should consult a doctor for 5 months. The use of the drug in children is recommended under the supervision of a physician. When adjusting stools for medical purposes, 20 g of the drug diluted in 1 liter of water are taken 3 times (at 12, 15 and 18 h) before medical procedures. In hepatic encephalopathy, hepatic precoma and coma, hyperammonemia, the dose of the drug should be selected individually for each patient, depending on the severity of the disease and the individual response to the drug. The initial daily dose is usually 500-700 mg / kg body weight. This dose is divided into 3 single doses. Accepted with meals. Should be selected dose, causing two soft chairs per day.
Side effects
At the beginning of treatment, there may be a feeling of discomfort in the abdomen, flatulence. These phenomena, as a rule, disappear with continued use of the drug, as it adapts to it. In the case of the use of the drug in high doses for a long time in the treatment of hepatic encephalopathy in a patient, due to diarrhea, an electrolyte imbalance may develop.
Overdose
Symptoms: diarrhea, in rare cases vomiting is possible. Treatment: Overdose symptoms are usually eliminated by lowering the dose of the drug.
Interaction with other drugs
At the same time taking Exportal with enteric preparations with a pH-dependent release, it should be taken into account that lactitol lowers the pH of the intestine. It is not recommended to use Export within 2 hours after taking other medicines.
special instructions
Lactitol has a low calorie content (2 kcal / g), does not affect blood glucose levels, and can be used in diabetic patients. Increased fluid intake is desirable throughout the entire course of use of the drug. Effects on driving ability of vehicles and driving mechanisms on psychomotor functions associated with driving a car or driving machines and mechanisms.