Fluomizin pillsvaginal 10mg N6
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Active ingredients
Dequalinium chloride
Release form
Pills
Composition
1 tablet contains: Active substance: dequalinium chloride 10 mg. Auxiliary substances: lactose monohydrate, microcrystalline cellulose, magnesium stearate.
Pharmacological effect
Fluomizin contains the active substance dequalinium chloride, which is a quaternary ammonium compound with a broad spectrum of antimicrobial activity. Dequalinium chloride is active against most Gram-positive bacteria Streptococcus spp., Including (beta-hemolytic streptococci of groups A and B), Staphylococcus aureus, Listeria spp .; anaerobes Peptostreptococcus (group D), fungi of the genus Candida (Candida tropicalis, Candida albicans, Candida glabrata), Gram-negative bacteria Gardnerella vaginalis, Escherichia coli, Serratia spp., Klebsiella spp., Pseudomonas spp., Proteus spp., Pseudomonas spp., Proteus spp., Klebsiella spp., Pseudomonas spp., Proteus spp., Pseudomonas spp., Proteus spp., Klebsiella spp., Pseudomonas spp., Proteus spp. ).
Pharmacokinetics
With intravaginal administration, an extremely small amount of dequalinium chloride is absorbed through the vaginal mucosa into the systemic circulation, is metabolized to the derivative of 2,2-dicarboxylic acid and excreted in an unconjugated form through the intestine.
Indications
- Bacterial vaginosis; - Candida vaginitis; - Trichomonas vaginitis; - Vaginal debridement before gynecological operations and childbirth.
Contraindications
- hypersensitivity to the components of the drug; - ulcerative lesions of the epithelium of the vagina and cervix. It is not recommended to use dequinium chloride before sexual activity.
Use during pregnancy and lactation
The drug is approved for use during the entire period of pregnancy and lactation.
Dosage and administration
The recommended dosage regimen is 1 vaginal tablet per day. A vaginal tablet is inserted deep into the vagina in the evening before bedtime, lying on your back, slightly bending your legs. During menstruation, treatment should be stopped and the previous course should be continued after it ends. You need to complete a full course of treatment (6 days) to avoid relapse.
Side effects
Extremely rarely, local irritation reactions (erosion), itching, burning or redness of the vaginal mucosa can be observed. However, these adverse reactions may also be associated with symptoms of a vaginal infection. Extremely rare fever, allergic reactions.
Overdose
Data overdose available. With intravaginal use, overdose is unlikely.
Interaction with other drugs
Fluomizin is incompatible with soap and other anionic surfactants.
special instructions
Fluomizin contains excipients that sometimes do not completely dissolve in the vagina. Therefore, residues of the vaginal pills can be found in underwear. This does not affect the effectiveness of Fluomizin. In rare cases, if the vagina is excessively dry, there is a chance that the tablet will remain undissolved. To prevent this, before introducing the vaginal tablet, it must be moistened with water (for 1 second under a stream of water). During the treatment period, it is recommended to change the pads and underwear more often. If the clinical signs of infection persist after completion of treatment, a microbiological examination should be carried out to identify the pathogen and confirm the diagnosis. During the period of treatment with the drug, it is recommended to refrain from sexual contact. To prevent urogenital reinfection, simultaneous treatment of sexual partners is necessary. Influence on the ability to drive vehicles and control mechanisms The drug does not affect the performance of potentially hazardous activities that require special attention and speed of psychomotor reactions (driving a car, etc.)