Galazolin nose drops 0.05% 10ml.
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Active ingredients
Xylometazoline
Composition
In 1 ml. . Xylometazoline hydrochloride 0.5 mg. Excipients: sodium hydrophosphate dodecahydrate - 2.5 mg, sodium dihydrogen phosphate monohydrate - 3.68 mg, sodium chloride - 3.3 mg, disodium edetate - 0.2 mg, benzalkonium chloride 50% - 0.2 mg, sorbitol - 20 mg, purified water - up to 1 ml.
Pharmacological effect
Vasoconstrictor drug for local use in ENT practice. Alpha-adrenomimetik from the group of imidazole derivatives. In low concentrations acts on? 2 -adrenoreceptors, in high concentrations has an effect on? 1 -adrenoreceptors. When applied topically, it causes narrowing of the blood vessels, which leads to a decrease in edema and hyperemia of the mucous membranes of the nasopharynx, reduces the amount of nasal secretions, and facilitates nasal breathing in rhinitis. The action of the drug begins after 5-10 minutes and lasts for 5-6 hours when used in the form of nasal drops and for 10 hours when used in the form of a nasal gel.
Indications
Acute rhinitis of viral or bacterial origin. - Allergic rhinitis. - acute sinusitis. - chronic sinusitis in the acute phase. - pollinosis. - otitis media (in order to reduce swelling of the mucous membrane of the nasopharynx and restore the patency of the Eustachian tube).
Use during pregnancy and lactation
Before use, you must clean the nasal passages. Galazolin. like other sympathomimetics, it should be used with extreme caution in patients with hypersensitivity to adrenomimetics, manifested by insomnia, dizziness, tremor, heart rhythm disturbances and increased blood pressure. Do not use the drug in patients with chronic or vasomotor rhinitis, because they have a tendency to use the drug for more than 5 days. Prolonged use of the drug (more than 2 weeks) can lead to secondary dilation of the blood vessels and subsequently to secondary medical rhinitis. The cause of this disease is the inhibition of the release of norepinephrine from nerve endings through the excitation of presynaptic? 2 receptors. Do not exceed the recommended dose, especially in children and elderly patients. The drug contains benzalkoniya chloride, and therefore may cause irritation of the nasal mucosa.
Dosage and administration
Galazolin. in the form of drops 0.05% is prescribed to children aged 2 to 6 years, 1-2 drops in each nostril 1-2 times / day.
Side effects
Incompatible with MAO inhibitors and tricyclic antidepressants. With simultaneous use of xylometazoline with other sympathomimetics (for example, ephedrine, pseudoephedrine), potentiation of the action occurs. Use this combination with caution.
special instructions
Incompatible with MAO inhibitors and tricyclic antidepressants. With simultaneous use of xylometazoline with other sympathomimetics (for example, ephedrine, pseudoephedrine), potentiation of the action occurs. Use this combination with caution.