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Active ingredients
Dexamethasone
Release form
Drops
Composition
On 1 ml: dexamethasone 1 mg. Excipients: benzalkonium chloride, hydroxypropyl methylcellulose, purified water.
Pharmacological effect
GKS for local use in ophthalmology. It has a pronounced anti-inflammatory, anti-allergic and desensitizing effect. Dexamethasone actively suppresses inflammatory processes by inhibiting the release of inflammatory mediators by eosinophils, the migration of mast cells and reducing the capillary permeability. The preparation does not possess mineralocorticoid activity.
Pharmacokinetics
Data on the pharmacokinetics of the drug Maxidex not provided.
Indications
- allergic blepharitis; - allergic conjunctivitis; - allergic keratoconjunctivitis; - acute and chronic iritis; - iridocyclitis; - prevention and treatment of inflammatory reactions in the postoperative period; - thermal and chemical burn (after complete epithelialization of corneal defects).
Contraindications
- viral, bacterial and fungal infections of the eye; - diseases of the cornea in combination with defects of the epithelium; - hypersensitivity to the components of the drug.
Use during pregnancy and lactation
During pregnancy, Maxidex should be prescribed only in cases where the expected therapeutic effect exceeds the potential risk to the fetus or child. If necessary, the appointment of the drug during lactation should be interrupted by breastfeeding.
Dosage and administration
The drug is instilled 1-2 drops in the conjunctival sac of the affected eye (or eyes) every 3-6 hours.
Side effects
On the part of the organ of vision: with prolonged local application of GCS, there may be noted: an increase in intraocular pressure with possible subsequent development of glaucoma; the formation of posterior subcapsular cataracts; slowing the wound healing process (in case of diseases that cause thinning of the cornea or sclera, perforation of the fibrous membrane is possible). After using drugs containing GCS, a secondary infection (including fungal infection) may develop, as a result of suppression of the patient’s defensive response. In acute purulent diseases, the eye corticosteroids can mask or enhance the existing infection process.The appearance of non-healing ulcers on the cornea after long-term treatment with steroid preparations may indicate the development of fungal invasion.
Overdose
Currently, no cases of overdose of Maxidex have been reported.
Interaction with other drugs
Clinically significant drug interaction of the drug Maxidex with other drugs is not installed.
special instructions
When using drugs containing GCS for more than 10 days, intraocular pressure should be measured regularly. The drug is intended for topical use only (it is not used for injection). During treatment, it is not recommended to wear contact lenses. avoid microbial contamination of the contents of the vial. Before use, shake the contents of the vial. Use in pediatrics Currently, the safety and effectiveness of the drug in etey not installed.