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Active ingredients
Metronidazole + Chlorhexidine
Release form
Gel
Composition
1 g of gel contains: Active substances: Metronidazole benzoate 16.0 mg (equivalent to metronidazole 10.0 mg) Chlorhexidine digluconate 20% solution 2.5 mg (equivalent to chlorhexidine digluconate 0.5 mg) and excipients: propylene glycol, carbomer- 940, disodium edetate, sodium saccharinate, levomenthol, sodium hydroxide, water.
Pharmacological effect
Efficiency is based on the presence of an antibacterial agent to anaerobic spheres, which cause periodontal disease: and antimicrobial agent, effective against gram-negative and gram-positive aerobic and anaerobic bacteria (Treponema spp., Neisseria gonorrhoeae, Trichomonas spp., Chlamydia spp., Ureaplasma spp., Bacteroides fragilis). To the drug weakly Some strains of Pseudomonas spp., Proteus spp. are also sensitive, as well as resistant acid-resistant forms of bacteria, bacterial spores. Does not violate the functional activity of lactobacilli. When applied topically, Metrogyl DENTA gel is practically not absorbed.
Indications
Infectious and inflammatory diseases of the periodontal and mucous membranes of the oral cavity: acute and chronic gingivitis, acute ulcerous-necrotic gingivitis of Vincent, acute and chronic periodontitis, adolescent periodontitis, periodontal disease complicated by gingivitis, aphthous stomatitis, I have a recurrent stenosis, a history of aphthous stomatitis, I have a stroke, has a recurrent anatomy, an afflictogenic stenitis, an inflammatory adenitis, an inflammatory disease post-extraction alveolitis (inflammation of the hole after tooth extraction), periodontitis, periodontal abscess (as part of combination therapy).
Contraindications
Individual intolerance to metronidazole, chlorhexidine, as well as derivatives of nitroimidazole. Intolerance to any components that make up the drug. Children's age up to 6 years.
Use during pregnancy and lactation
It is not recommended to prescribe the drug to pregnant women in the first trimester of pregnancy. During lactation, if necessary, the appointment of the drug, should decide on the termination of breastfeeding.
Dosage and administration
Locally, only for dental use. Adults and children over 6 years old with inflammation of the gums (gingivitis) Metrogyl DENTA is applied to the gum area with a thin layer with a finger or using a cotton swab 2 times a day. After applying the gel should refrain from drinking and eating for 30 minutes.Rinse the gel is not recommended. The duration of treatment is on average 7 - 10 days. In periodontitis after removal of dental deposits, periodontal pockets are treated with Metrogyl DENT gel and gel is applied to the gum area. Exposure time - 30 minutes. The number of procedures depends on the severity of the disease. In the future, the gel can be applied by the patient on its own: Metrogyl DENTA is applied to the gum area 2 times a day for 7-10 days. within 7-10 days. To prevent exacerbations of chronic gingivitis and periodontitis, Metrogyl DENT gel is applied to the gum area 2 times a day for 7-10 days. Preventive treatments are carried out 2-3 times a year. For the prevention of post-extraction alveolitis after extraction of the tooth, the hole is treated with Metrogyl DENT gel, then the gel is applied 2-3 times a day for 7-10 days.
Side effects
With topical application of Metrogyl DENT gel, allergic reactions (skin rash, itching, urticaria), as well as headache can be observed.
Overdose
Accidental or deliberate ingestion of a large amount of gel can lead to increased side effects, mainly caused by metronidazole (chlorhexidine is practically not absorbed from the gastrointestinal tract). There may be: nausea, vomiting, dizziness, in more severe cases, paresthesias and convulsions. Treatment: gastric lavage, if necessary symptomatic therapy.
Interaction with other drugs
When applied topically at the recommended doses, systemic interaction of Metrogyl DENTA gel with other drugs was not detected.
special instructions
The use of Metrogyl DENTA gel does not replace hygienic cleaning of teeth, therefore, during the course of treatment with the preparation, cleaning of teeth should be continued.