Naftizin plus nasal drops 0.05% 15ml
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Active ingredients
Naphazoline
Release form
Drops
Composition
The composition of the drug in 1 ml of 0.1% Active substance: Naphazoline nitrate 1.0 mg (naphthyzinum) Excipients: Boric acid 20 mg, Sea water 5 mg, 0.1 M solution of sodium hydroxide to pH 4.5 - 6.0 Water for injection up to 1 ml
Pharmacological effect
Alpha2-adrenomimetik, has a fast, pronounced and prolonged vasoconstrictor effect on the vessels of the nasal mucosa (reduces swelling, hyperemia, exudation). Relieves nasal breathing in rhinitis. After 5-7 days, tolerance arises.
Pharmacokinetics
When applied topically, systemic absorption is low. Vasoconstrictor effect occurs after a few minutes and lasts for several hours.
Indications
Acute rhinitis, allergic rhinitis, sinusitis, eustachitis. To facilitate rhinoscopy.
Contraindications
Hypersensitivity to the drug components, arterial hypertension, marked atherosclerosis, hyperthyroidism, chronic rhinitis, severe eye diseases, diabetes mellitus, tachycardia, simultaneous administration of monoamine oxidase inhibitors and a period of up to 14 days after the end of their use, up to 1 year old (for 0.05% solution), age up to 15 years (for a 0.1% solution).
Precautionary measures
Ischemic heart disease (angina), prostatic hyperplasia, pheochromocytoma, pregnancy, breastfeeding period.
Use during pregnancy and lactation
Use for the treatment of pregnant women and during breastfeeding is possible only if the expected benefit to the mother outweighs the potential risk to the fetus and child.
Dosage and administration
Apply intranasally (in each nasal passage). Adults and children over 15 years old are prescribed 1-3 drops of a 0.05-0.1% solution of the drug 3-4 times a day. Children use 0.05% solution: from 1 to 6 years - 1-2 drops, from 6 to 15 years - 2 drops 1-3 times a day. For diagnostic purposes, after cleaning the nose, drip 3-4 drops into each nasal passage or introduce a tampon dipped in 0.05% solution and leave for 1-2 minutes. With rhinitis, the treatment should not exceed 5-7 days in adults and no more than 3 days in children.
Side effects
From the side of the central nervous system: headache.Since the cardiovascular system: tachycardia, increased blood pressure, reactive hyperemia. On the part of the digestive system: nausea. Local reactions: irritation, swelling of the mucous membrane of the nasal cavity, when used for more than 1 week - swelling of the mucous membrane of the nasal cavity, atrophic rhinitis.
Overdose
Symptoms: decrease in body temperature, bradycardia, increased blood pressure. Treatment: symptomatic.
Interaction with other drugs
It should not be used simultaneously with monoamine oxidase inhibitors or within 14 days after the end of their use. Slows down the absorption of local anesthetic drugs (lengthens their action when performing surface anesthesia). Co-administration of other vasoconstrictor drugs increases the risk of side effects.
special instructions
May have a resorptive effect. With prolonged use, the severity of the vasoconstrictive action gradually decreases (the phenomenon of tachyphylaxis), and therefore it is recommended to take a break for several days after 5-7 days of use. Impact on the ability to drive vehicles and mechanisms Not identified.