Posterisan forte suppositories rectal 10 pieces
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Active ingredients
Inactivated microbial cells of E. coli + Hydrocortisone
Release form
Suppositories
Composition
The active component of the drug are corpuscular components and metabolic products of Escherichia coli and hydrocortisone. 1 g of ointment contains 166.7 mg of an aqueous suspension of 500 million E. coli (particulate constituents and metabolic products) and 3.3 mg of liquid phenol (respectively 3.0 mg of pure phenol) as a preservative and 2.5 mg hydrocortisone. Excipients: lanolin, petrolatum.
Pharmacological effect
The drug stimulates the processes of local immunity due to antigenic action, causing both non-specific and specific immune responses. Accelerates and improves wound healing, has anti-inflammatory effect, prevents reinfection and superinfection.
Indications
Hemorrhoids (mainly suppositories), perianal dermatitis (ointment), anal and genital itching, especially resistant to other drugs, anopapillitis, anal fissure (ointment), condition after operations on the anorectal region (to stimulate wound healing).
Contraindications
Hypersensitivity to phenol.
Precautionary measures
Treatment continues until the symptoms disappear, but not longer than 5-7 days. When treating with a drug due to a Vaseline excipient, while using condoms at the same time, it can lead to a decrease in tensile strength and, consequently, to a decrease in the reliability of such condoms.
Use during pregnancy and lactation
Glucocorticosteroids cross the placenta. To date, there are no clear data on the development of teratogenic effects in humans, similar to those observed in animal studies. With systemic use of large doses of corticosteroids, effects on the fetus or newborn have been reported (growth retardation in the uterus, adrenocortical suppression). Despite the small amount of information regarding the use of corticosteroids as an ointment during pregnancy, given their limited systemic absorption, it is possible to use corticosteroids of mild and moderate action (class 1 and class 2), such as hydrocortisone, for short periods of time and on limited skin areas .The above effects can not be excluded with prolonged use or application to large areas of skin. This can only be done with special indications. During the period of breastfeeding can be used only with short-term treatment and application of small. plots. When long-term treatment or application to large areas of the affected skin should stop breastfeeding.
Dosage and administration
Rectal suppositories in the acute period of the disease are used 2-3 pieces. per day. After elimination of the subjective symptoms of the disease, the affected area continues to be lubricated 1 time per day or 1 supp is administered. 1 time per day for several days. If Posterisan Forte is used to treat chronic dermatitis, then after the disappearance of skin manifestations, it is recommended to extend the therapy for another 1-2 weeks. Perhaps the combined use of ointments and suppositories. After completing the course of treatment, it is advisable to use the drug (ointment or suppository), which does not contain hydrocortisone, for another 2-3 weeks to consolidate the therapeutic effect.
Side effects
Rarely, allergic reactions (associated with the use of phenol as a preservative).
Overdose
No cases of overdose or intoxication were reported. Overdose causes suppression of the function of the hypothalamic-pituitary-adrenal system. In case of accidental oral administration of the ointment (for example, in children), this can lead to gastrointestinal upset (abdominal pain, nausea).
Interaction with other drugs
With the simultaneous use of “Posterizan Forte” ointment with other drugs containing corticosteroids (in the form of pills, drops or solutions for injection), the therapeutic and side effects of glucocorticosteroids may be enhanced.
special instructions
The ability to influence the reaction rate when driving vehicles or machinery. No data available