Sodium Chloride Injection Ampoule 0.9% 5ml N10
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Active ingredients
Sodium chloride
Release form
Solution
Composition
Sodium chloride 9 g excipients: water for injection - up to 1 l
Pharmacological effect
Detoxification
Pharmacokinetics
Sodium concentration - 142 mmol / l (plasma) and 145 mmol / l (interstitial fluid), chloride concentration - 101 mmol / l (interstitial fluid). Excreted by the kidneys.
Indications
Large losses of extracellular fluid or insufficient intake of it (toxic dyspepsia, cholera, diarrhea, "indomitable" vomiting, extensive burns with severe exudation, etc.); hypochloremia and hyponatremia with dehydration; intestinal obstruction; intoxication; washing of wounds, eyes, nasal mucosa, dissolution and dilution of drugs and moistening dressing
Contraindications
Hypernitraemia; acidosis; hyperchloremia; hypokalemia; extracellular overhydration; intracellular dehydration; circulatory disorders threatening swelling of the brain and lungs; swelling of the brain; pulmonary edema; acute left ventricular failure; concomitant administration of large doses of corticosteroids. With care: renal failure; heart failure; oligo and anuria
Precautionary measures
With caution apply large amounts of sodium chloride in patients with impaired renal excretory function, with hypokalemia. The introduction of large quantities of the solution can lead to chloride acidosis, overhydration, an increase in the excretion of potassium from the body. Hypertonic solution is not used s / c and v / m. With long-term use, it is necessary to control the concentration of electrolytes in the plasma and daily diuresis. The temperature of the infusion solution should be 38 ° WITH
Use during pregnancy and lactation
Allergies in pregnant women after administration of this drug has not been fixed
Dosage and administration
Isotonic solution of sodium chloride is administered in / in, p / to and in enemas, and also used for washing wounds, eyes, nasal mucosa. Often administered in / in, depending on the clinical situation - up to 3 l / day. Hypertonic sodium chloride solution is administered in / in. A single dose for IV injection may be 10-30 ml. In conditions requiring immediate replacement of sodium ions and chlorine, the drug is administered in / in a drip in a dose of 100 ml.Locally and externally used depending on the dosage form and treatment regimen used
Side effects
Possible: nausea, vomiting, diarrhea, stomach cramps, thirst, lacrimation, sweating, fever, tachycardia, arterial hypertension, impaired kidney function, swelling, shortness of breath, headache, dizziness, anxiety, weakness, twitching and hypertension of muscles. When external and local use, adverse reactions have not yet been established.
Overdose
No data on drug overdose
Interaction with other drugs
When mixed with other drugs, you need to visually monitor compatibility.
special instructions
Perhaps the freezing of the drug under the condition of the integrity of the tightness of the container. Non-wettability of the inner surface of the bottle is not a contraindication to the use of the drug