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Active ingredients
Metamizole sodium + Pitofenon + Fenpiverinium bromide
Release form
Pills
Composition
1 tablet of the drug Spasmalgon contains: Metamizole sodium - 500 mg; Pitofenone hydrochloride - 5 mg; Fenpiverinium bromide - 0.1 mg; Auxiliary substances, including lactose monohydrate.
Indications
Pharmacokinetics
Contraindications
The drug Spasmalgon in the form of pills is used for symptomatic treatment of patients suffering from weak or moderate intensity pain, including the drug indicated for such diseases: Urinary tract diseases that are accompanied by pain and urination disorders, including inflammatory diseases of the urinary system and urinary tract disease. Gastric and intestinal colic, diseases of the digestive tract organs, which are accompanied by spasm of smooth muscles to biliary tract dyskinesia, cholelithiasis. Spasmalgon preparation in tablet form is also used to relieve pain syndrome of weak or moderate intensity with primary and secondary dysmenorrhea. If necessary, the drug can be used for symptomatic treatment of pain syndrome in patients suffering diseases of the musculoskeletal system and neuralgia. However, in this case, the drug is recommended for short periods. The Spasmalgon preparation in the form of injection solution is used to relieve pronounced pain syndrome caused by spasms of smooth muscles, including: Spasm of smooth muscles of the ureter and bladder, as well as renal colic, which are accompanied by pain syndrome of the weak and moderate intensity. Diseases of the liver and biliary tract, which are accompanied by severe pain, including hepatic (biliary) colic, dyskinesia, chewing pathways, sphincter Oddi dysfunction (postcholecystectomy syndrome). Diseases of the gastrointestinal tract, which are accompanied by pains of a spastic nature, including intestinal colic and chronic colitis. Diseases of the pelvic syndrome, which are accompanied by pain syndrome of weak and moderate intensity. primary and secondary dysmenorrhea.
Use during pregnancy and lactation
Metamizol, which is part of the Spasmalgon preparation, is an enzyme inducer, therefore the simultaneous use of the Spasmalgon preparation with other drugs should be carried out under the strict supervision of the attending physician. during the period of drug therapy Spazmalgon. With simultaneous use of the drug reduces the effectiveness of coumarin anticoagulants. At the same time When using the drug with phenothiazine derivatives, including chlorpromazine, there is a risk of developing severe hypothermia. Spasmalgon reduces the plasma concentrations of cyclosporine when used simultaneously. with myelotoxic effect. Barbititurates, phenylbutazone and other enzyme inducers with simultaneous application of The therapeutic effect of Metamizole. With simultaneous use of the drug with tricyclic antidepressants, allopurinol and artificial contraceptives, there is an increase in the toxic effect of Metamizole. Non-steroidal anti-inflammatory drugs with simultaneous use with the Spasmalgon drug increase the risk of side effects. sedative drugs. When combined with An increase in anticholinergic action is noted when using a drug containing quinine. Spasmalgon preparation in the form of injection solution should not be mixed with other injection solutions in one syringe. The combination of Spasmalgon with furosemide, glibenclamide and hyoscinbutyl bromide is allowed.
Dosage and administration
pharmachologic effect
Side effects
- Increased individual sensitivity to the components of the drug and other drugs of the group of non-steroidal anti-inflammatory drugs; - increased individual sensitivity to pyrazolone derivatives; - suspicion of surgical pathology; -dysfunction of the hematopoietic system, including agranulocytosis, leukopenia, aplastic anemia; - the drug is contraindicated in patients suffering from severe hepatic and / or renal failure, acute hepatic porphyria, as well as decreased urinary and / or gall bladder tone; - the drug is not prescribed to patients , suffering from closed-angle glaucoma, tachyarrhythmia and deficiency of glucose-6-phosphate dehydrogenase; - spasmalgon is contraindicated in case of obstruction of the gastrointestinal tract, megacolon, collaptoid states. In addition, the drug is not prescribed to patients suffering from prostate adenoma, which is accompanied by urination disorders. It is not recommended to prescribe the drug to women during pregnancy and lactation, as well as to children under the age of 15. The drug is prescribed with caution to patients with hay fever, bronchial asthma and allergic rhinitis, since they have an increased risk of hypersensitivity reactions. The drug is prescribed with caution to patients suffering from liver and / or kidney diseases, obstructive abdominal diseases of the gastrointestinal tract, gastroesophageal reflux disease, decreased intestinal tone, glaucoma, paralytic ileus and diseases of the cardiovascular system. The drug should be prescribed with caution to patients whose work is related to the management of potentially dangerous mechanisms and driving a car.
Overdose
Precautionary measures
Interaction with other drugs
The drug Spazmalgon in the form of pills is taken orally, the tablet is swallowed whole, without grinding and chewing, drinking plenty of water. If necessary, the tablet can be divided. The duration of the course of treatment and the dose of the drug are determined by the attending physician individually for each patient, depending on the nature of the disease and the patient’s individual characteristics. For the treatment of spastic pain, adults and adolescents over 15 years of age usually prescribe 1-2 pills 2-3 times a day . It is not recommended to take more than 6 pills of the drug per day. For the treatment of pains of a spastic nature, children between the ages of 13 and 15 usually prescribe 1 tablet of the drug 2-3 times a day.It is not recommended to take more than 3 pills of the drug per day. For the treatment of pains of a spastic nature, children at the age of 9 to 12 years old usually take 1/2 tablet of the drug 2-3 times a day. It is not recommended to take more than 2 pills of the drug per day. The drug is not recommended to be taken for more than 3 days in a row if the treating physician has not prescribed it differently. The Spasmalgon preparation in the form of injection solution is used only for intramuscular administration. The duration of the course of treatment and the dose of the drug are determined by the attending physician individually for each patient, depending on the nature of the disease and the patient’s individual characteristics. Adults and adolescents over the age of 15 years are usually prescribed 2-5 ml of the drug 2-3 times a day. It is recommended to observe the interval between injections of the drug for at least 6 hours. It is not recommended to inject more than 10 ml of the drug per day. The drug is not recommended to be taken for more than 3 days in a row if the attending physician has not prescribed otherwise. If there is no necessary therapeutic effect, the use of the drug is stopped. If there is a positive trend, therapy is continued with the preparation Spasmalgon in the form of pills.