Spiramycin-prob coated pills 3 million IU N10
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Active ingredients
Spiramycin
Release form
Pills
Composition
Spiramycin 3 million
Pharmacological effect
Spiramycin-prob has antibacterial, bacteriostatic action.
Indications
Bacterial infections caused by susceptible microorganisms: acute community-acquired pneumonia (including atypical ones caused by Mycoplasma, Chlamydia, Legionella), exacerbation of chronic bronchitis; sinusitis, tonsillitis, otitis media; osteomyelitis, arthritis; extragenital chlamydia, prostatitis, urethritis of various etiologies; sexually transmitted diseases; skin infections: erysipelas, infected dermatosis, abscess, phlegmon (including in dentistry); toxoplasmosis, incl. during pregnancy; prevention of meningococcal meningitis among those who have been in contact with patients no more than 10 days before his hospitalization; prevention of acute articular rheumatism; treatment of bacterial carriers of pertussis and diphtheria pathogens.
Contraindications
Hypersensitivity to spiramycin and other components Spiramycin-ven; breastfeeding period; children's age (pills of 3 million ME in children do not apply); The use of spiramycin in patients with deficiency of the enzyme glucose-6-phosphate dehydrogenase is not recommended due to the possible occurrence of acute hemolysis.
Dosage and administration
Spiramycin-probably taken by mouth. Adults - 2-3 table. 3 million IU (ie 6-9 million ME) per day in 2 or 3 doses. The maximum daily dose - 9 million ME. Prevention of meningococcal meningitis - 3 million IU for 12 hours in 5 days.
Side effects
On the part of the gastrointestinal tract: nausea, vomiting, diarrhea and very rare cases of pseudomembranous colitis (less than 0.01%). Isolated cases of ulcerative esophagitis and acute colitis are described. The possibility of the development of acute damage to the intestinal mucosa in patients with AIDS when using high doses of spiramycin for cryptosporidiosis was also noted. From the peripheral system and central nervous system: transient paresthesia. Co side of the liver: in very rare cases (less than 0.01%) - changes in liver function tests and the development of cholestatic hepatitis. From the side of blood-forming organs: very rare cases (less than 0.01%) of the development of acute hemolysis and thrombocytopenia. Since the cardiovascular system: possible prolongation of the QT interval on the electrocardiogram.Hypersensitivity reactions: skin rash, urticaria, pruritus. Very rarely (less than 0.01%) - angioedema, anaphylactic shock.