Vicks asset synex spray nazal 0.05% 15ml
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Active ingredients
Oxymetazoline
Release form
Spray
Composition
Active ingredient: Oxymetazoline. Additional substances: sorbitol (70% aqueous solution) 5.0 g, sodium citrate dihydrate 0.875 g, tyloxapol 0.7 g, chlorhexidine digluconate (20% solution) 0.27 g, anhydrous citric acid 0.2 g, aloe vera 0.1 g, benzalkonium chloride (50% solution) 0.04 g, levomenthol 0.015 g, potassium acesulfame 0.015 g, cyneol 0.013 g, L-carvone 0.01 g, disodium edetate 0.01 g, sodium hydroxide ( 0.1 M solution) to pH 5.4, distilled water to 100 ml. Concentration of the active substance (mg): 0.5 mg
Pharmacological effect
Vasoconstrictor drug for local use, alpha-adrenostimulyator. has a vasoconstrictor effect. with intranasal administration reduces the swelling of the mucous membrane of the upper respiratory tract, which leads to the relief of nasal breathing and the opening of the mouths of the paranasal sinuses and Eustachian tubes. the effect of the drug appears 5 minutes after application and lasts for 8-12 hours.
Pharmacokinetics
When applied topically, oxymetazoline is practically not absorbed.
Indications
For relief of nasal breathing with colds or viral infections of the upper respiratory tract, sinusitis, rhinitis of any etiology.
Contraindications
hypersensitivity to the components of the drug, atrophic (dry) rhinitis, taking monoamine oxidase inhibitors (MAO) during the previous 2 weeks and 2 weeks after their withdrawal, angle-closure glaucoma, post-transsphenoidal hypophysectomy, children up to 6 years of age; pregnancy, lactation
Precautionary measures
The drug should be stored out of the reach of children at a temperature not higher than 25 ° C.
Use during pregnancy and lactation
The drug is contraindicated during pregnancy and lactation (breastfeeding).
Dosage and administration
Intranasal. Adults and children over 10 years old - 1-2 injections into each nasal passage maximally 2-3 times a day. Children from 6 to 10 years old - 1 injection in each nasal passage maximally 2-3 times a day. Duration of treatment: It is not recommended to use the drug for more than 7 days. With frequent or prolonged use of the drug, a feeling of difficulty in nasal breathing may recur or worsen.If these symptoms appear, you should stop treatment and consult a doctor. When injecting, do not tilt the head backwards or spray in the prone position.
Side effects
Sometimes burning or dryness of the mucous membranes of the nose, dryness in the mouth and throat, sneezing, an increase in the volume of secretions released from the nose. In rare cases, after the effect of using the drug has passed, a strong feeling of nasal congestion (reactive hyperemia). Side effects caused by the systemic effect of the drug: increased blood pressure, headache, dizziness, heart palpitations, tachycardia, increased anxiety, sedation, irritability, sleep disturbances (in children), nausea, insomnia, exanthema, impaired vision (eye contact) ). Preservative benzalkoniya chloride, which is part of the drug, may be the cause of swelling of the nasal mucosa. If this happens, you need to change the drug to another, not containing preservatives.
Overdose
Symptoms: nausea, increased blood pressure, tachycardia, CNS depression. Treatment: symptomatic therapy.
Interaction with other drugs
With simultaneous use with MAO inhibitors (including a period of 14 days after their withdrawal) and tricyclic antidepressants, an increase in blood pressure may be observed. The drug slows down the absorption of local anesthetic drugs, lengthens their action. Combining other vasoconstrictive drugs increases the risk of side effects.
special instructions
At the recommended dose without consultation with the doctor, use no more than 7 days. If the symptoms worsen or the improvement does not occur within 3 days, the patient should consult with the doctor. To avoid contact with the eye.