Gynalgin vaginal pills N10
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Active ingredients
Metronidazole
Release form
Pills
Composition
1 tab. metronidazole 250 mg chlorochinaldol 100 mg. Excipients: lactose monohydrate, corn starch, talc, anhydrous colloidal silicon dioxide, magnesium stearate. The composition of the capsule shell: gelatin, methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), diamond black dye (E151), black iron oxide (E172), titanium dioxide (E171), orange dye (E110), quinoline yellow (E 104).
Pharmacological effect
Combined preparation for intravaginal use. It has antibacterial, antiprotozoal and antifungal effects. Metronidazole refers to nitro-5-imidazoles. Restores the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa, which interact with the cell DNA of microorganisms, inhibiting the synthesis of their nucleic acids, which leads to the death of microorganisms. It is an effective antimicrobial and antiprotozoal agent of a wide spectrum of action. It is active against Trichomonas vaginalis, Giardia intestinalis, Entamoeba histolytica, Lamblia intestinalis, as well as with respect to obligate anaerobes (spore-and non-sporiferous) - Bacteroides spp. (V. fragilis, B. ovatus, B. distasonis, B. thetaiotaomicron, B. vulgatus), Fusobacterium spp., Clostridium spp., Peptostreptococcus spp., Sensitive Eubacterium strains. He sensitive aerobic microorganisms and facultative anaerobes. Chlorquinaldol acts on the following strains of pathogenic bacteria: Corynebacterium diphtheria, Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris, Salmonella spp., Shigella spp., Escherichia coli. It also exhibits activity with respect to the simplest: Entamoeba histolytica, Lamblia intestinalis, Trichomonas vaginalis and some fungi. Citric acid reduces the pH of the vagina, promotes the growth and reproduction of Doderlein sticks.
Indications
Treatment - bacterial vaginitis. - Trichomonas vaginitis. - fungal vaginitis. - Vaginitis caused by mixed flora. Prevention - before the surgical treatment of gynecological diseases. - before childbirth and abortion. - before and after the introduction of intrauterine contraceptives. - before and after coagulation of the cervix. - before hysterography.
Contraindications
- hypersensitivity to the components of the drug - blood disorders - impaired coordination of movements, organic lesions of the central nervous system (including epilepsy) - liver failure (in the case of large doses), - pregnancy - breastfeeding period.
Use during pregnancy and lactation
The drug is contraindicated in pregnancy and lactation (breastfeeding).
Dosage and administration
1 vaginal tablet per day, for 7-10 days. Treatment begins 2-4 days after menstruation. The tablet should be inserted deep into the vagina, preferably in the evening before bedtime. If necessary, may conduct a second course of treatment.
Side effects
Local reactions: itching, burning, pain and irritation in the vagina. thick, white, mucous discharge from the vagina without odor or with a faint odor, frequent urination. after discontinuation of the drug - the development of vaginal candidiasis. The sensation of burning or irritation of the penis of the sexual partner. On the part of the gastrointestinal tract: nausea, change in taste, metallic taste in the mouth, dry mouth, decreased appetite, spastic abdominal pain, nausea, vomiting, constipation or diarrhea. Allergic reactions: urticaria, itchy skin, rash. From the side of the central nervous system: headache, dizziness. Other: leukopenia or leukocytosis. urine staining in red-brown color, due to the presence of water-soluble pigment, resulting from the metabolism of metronidazole. In the event of any undesirable side effects, you must stop treatment and consult a doctor.
special instructions
Local reactions: itching, burning, pain and irritation in the vagina. thick, white, mucous discharge from the vagina without odor or with a faint odor, frequent urination. after discontinuation of the drug - the development of vaginal candidiasis. The sensation of burning or irritation of the penis of the sexual partner. On the part of the gastrointestinal tract: nausea, change in taste, metallic taste in the mouth, dry mouth, decreased appetite, spastic abdominal pain, nausea, vomiting, constipation or diarrhea. Allergic reactions: urticaria, itchy skin, rash. From the side of the central nervous system: headache, dizziness. Other: leukopenia or leukocytosis. urine staining in red-brown color, due to the presence of water-soluble pigment, resulting from the metabolism of metronidazole. In the event of any undesirable side effects, you must stop treatment and consult a doctor.