More info
Active ingredients
Aluminum hydroxide + Magnesium hydroxide + Simethicone + Licorice root extract
Release form
Suspension
Composition
5 ml of suspension contain: Active substances: aluminum hydroxide gel 6 g, magnesium hydroxide 80 mg, simethicon 100 mg, powder of licorice root 400 mg, Excipients: guar gum, sorbitol, sodium benzoate, sodium citrate, methylparaben, propyl paraben, sodium saccharinate, sodium hypochlorite , sodium hydroxide, peppermint oil, banana flavor, bronopol, purified water.
Pharmacological effect
Antacid with a component that reduces flatulence. Neutralizes the free hydrochloric (hydrochloric) acid in the stomach, which leads to a decrease in the activity of pepsin. Does not cause secondary hypersecretion of gastric juice. It has an adsorbing and enveloping effect, reduces the influence of damaging factors on the gastric mucosa. Accelerates the healing of gastric and duodenal ulcers. Reduces flatulence in the intestines. Simethicone, which is part of the drug, reduces flatulence in the intestines. Licorice root extract degracirinised enhances the protective effect on the gastric mucosa, promoting the regeneration of mucous cells, improving the quality and quantity of mucus, and also has an antispasmodic effect. The drug accelerates the healing of gastric and duodenal ulcers.
Pharmacokinetics
The absorption of the components of the drug is low.
Indications
Peptic ulcer of the stomach and duodenum in the acute phase. Acute gastritis. Chronic gastritis with increased and normal secretory function in the acute phase. Duodenitis. Esophageal hernia. Esophagitis. Discomfort and epigastric pain with error in the diet, after taking medications , drinking coffee, nicotine and alcohol.
Contraindications
Fructose intolerance. Hypophosphatemia. Disturbed kidney function. Alzheimer's disease. Pregnancy. Lactation (breastfeeding). Children under 10 years old. Increased sensitivity to the components of the drug.
Precautionary measures
On the part of the digestive system: constipation, nausea, vomiting, stomach cramps, changes in taste.From the side of water and electrolyte balance: hypermagnesium, hypophosphatemia, hypocalcemia, hypercalciuria, hyperaluminiemia. From the urinary system: nephrocalcinosis, impaired renal function. From the musculoskeletal system: osteomalacia, osteoporosis.
Use during pregnancy and lactation
The drug is contraindicated for use in pregnancy. If necessary, the use of the drug during lactation should decide on the termination of breastfeeding.
Dosage and administration
For adults and adolescents over 15 years old, the drug is prescribed in 5-10 ml (1 / 2-1 dosage cup) 3-4 Maximum daily dose is 40 ml (4 dosage cups). For children aged 10 to 15, the recommended dose is 1 / 2 from the recommended adults. The duration of therapy is 14 days. The question of a more prolonged use is decided by the doctor individually. The drug is taken 1 hour after a meal and in the evening before going to bed or if discomfort occurs, epigastric pain, heartburn. Before taking it, the suspension should be homogenized by shaking the vial.
Side effects
Hypersensitivity to the components of the drug. Fructose intolerance. Hypophosphatemia. Severe renal dysfunction. Alzheimer's disease. Pregnancy. Breastfeeding period.
Overdose
Symptoms: with prolonged use in high doses, the formation of kidney stones, constipation, drowsiness, hypermagnemia; development of signs of metabolic alkalosis (changes in mood, muscle pain, nervousness, fatigue, unpleasant taste sensations). Treatment: gastric lavage, artificial vomiting, reception of activated carbon.
Interaction with other drugs
Relzer with simultaneous use can adsorb some drugs, thus reducing their absorption. Relcer reduces and slows down the absorption of digoxin, indomethacin, salicylates, chlorpromazine, phenytoin, histamine H2 receptor blockers, beta-adrenergic blockers, diflunisal, isoniazid, tetracycline antibiotics, quinolones (ipc, 172, 152, 202 , azithromycin, cefpodoxime, pivampicillin, rifampicin, indirect anticoagulants, barbiturates, fexofenadine, dipyridamole, zalcitabine, bile acids (chenodesoxycholic and ursodesoxycholic), penicillamine, drug iron and lithium, quinidine, lansoprazole, mexiletine, ketoconazole.When taken simultaneously with drugs in enteric dosage forms, a change in the pH of the gastric juice (more alkaline reaction) can lead to accelerated destruction of the membrane and cause irritation of the mucous membrane of the stomach and duodenum. With the joint use of m-anticholinergic drugs, slowing gastric emptying, strengthen and lengthen the effect of the drug Relcer.
special instructions
The interval between taking Reltsera and other medicines should be 1-2 hours. With long-term use (more than 14 days) regular medical supervision is necessary. The drug contains sorbitol and is therefore contraindicated in fructose intolerance.