More info
Active ingredients
Diflucortolon + Isoconazole
Release form
Cream
Composition
Active ingredient: diflucortolone valerate - 0.1 g, isoconazole nitrate -1.0 g Supporting substances: polysorbate 60-3.5 g, sorbitan stearate -1.0 g, cetostearyl alcohol (cetyl alcohol 60%, stearyl alcohol 40%) - 5.0 g, liquid paraffin -10.0 g, white petrolatum -10.0 g, disodium edetate -0.1 g, purified water -69.3 g. Active substance concentration (mg): 1100 mg
Pharmacological effect
Combined preparation for external use. Isoconazole is a synthetic imidazole derivative. has antifungal and antibacterial action. fungicidal and bactericidal. inhibits the synthesis of ergosterol cell membranes of the fungus, causing its death, blocks the synthesis of bacterial proteins. dermatophytes (trichophyton spp., microsporum spp., apros), molds, yeast and yeast-like fungi (candida spp., pityrosporum orbiculare / ovale), corynebacterium minutissium (erythromasma, ats, aus), ats, aus, ophthalmus , staphylococcus spp.). Diflucortolone valerate - GX for external use. has anti-inflammatory, antiexudative, antiallergic and antipruritic action.
Pharmacokinetics
Pharmacokinetics studies have not been conducted.
Indications
Dermatoses of combined etiology sensitive to glucocorticosteroid therapy, infected with fungal / bacterial flora. Fungal lesions of the skin, including those that are secondarily infected, accompanied by severe inflammatory or eczema-like symptoms: - mycoses of the feet and smooth skin, including localization in the folds, interdigital spaces, the external genitalia (including balanoposthitis): microsporia, trichophytosis, rubrofitiya, athlete; - Candidomycosis; - Erythrasma.
Contraindications
Hypersensitivity to the drug. Tuberculosis, syphilitic, viral (chicken pox, shingles) skin lesions, skin post-vaccination reactions, pregnancy - I trimester, children under 2 years old. With caution - pregnancy II and III trimester, lactation.
Precautionary measures
The drug should be stored out of reach of children at a temperature not exceeding 25 ° C.
Use during pregnancy and lactation
With caution should be prescribed the drug in the II and III trimesters of pregnancy and lactation. Contraindicated in the first trimester of pregnancy.
Dosage and administration
Outwardly.Grass is applied in a thin layer on the affected skin and lightly rubbed 2 times a day (morning and night). The maximum duration of treatment is 2 weeks.
Side effects
Travocort is usually well tolerated, even when applied to sensitive skin. In rare cases, skin irritation and allergic reactions may develop. Considering that the drug contains a glucocorticosteroid for external use, when applying the cream on large surfaces (more than 10% of the skin surface), for a long time (more than 4 weeks) and / or when using an occlusive dressing, the appearance of side effects characteristic of glucocorticosteroids may occur : atrophy of the skin, telangiectasia, striae, acne-like dermatitis, perioral dermatitis, hypertrichosis, as well as systemic side effects (suppression of the function of the hypothalamic-pituitary-adrenal system).
Overdose
Symptoms of acute overdose are not described, however, with excessive or prolonged use of the drug may be a chronic overdose, accompanied by the described adverse reactions. Treatment: symptomatic therapy is carried out.
Interaction with other drugs
Not found.
special instructions
The drug is intended for external use only. Avoid contact with the eyes and apply to open wounds. In case of accidental ingestion of the drug in the eyes, rinse thoroughly with warm water. In patients with rosacea or perioral dermatitis, the preparation should be avoided on the skin. The effect on the ability to drive vehicles and control mechanisms is not detected.