Acetylcysteine effervescent 600mg N12 pills
Condition: New product
1000 Items
Rating:
Be the first to write a review!
More info
Active ingredients
Acetylcysteine
Release form
Pills
Composition
Effervescent pills of white or almost white color, round, flat-cylindrical, with a chamfer, a rough surface and a weak characteristic odor. 1 tab. acetylcysteine 600 mg Auxiliary substances: ascorbic acid - 25 mg, sodium anhydrous carbonate - 93 mg, sodium bicarbonate - 724 mg, anhydrous citric acid - 765 mg, sorbitol - 695 mg, macrogol 6000 - 70 mg, sodium citrate - 500 mg, sodium Saccharinate - 8 mg, lemon flavor - 20 mg.
Pharmacological effect
Mucolytic agent, is derived from the amino acid cysteine. It has a mucolytic effect, facilitates sputum discharge due to a direct effect on the rheological properties of sputum. The action is due to the ability to break the disulfide bonds of the mucopolysaccharide chains and cause the depolymerization of the mucoproteins of sputum, which leads to a decrease in the viscosity of the sputum. The drug retains activity in the presence of purulent sputum. It has an antioxidant effect, due to the ability of its reactive sulfhydryl groups (SH-groups) to bind with oxidative radicals and, thus, neutralize them. In addition, acetylcysteine contributes to the synthesis of glutathione, an important component of the antioxidant system and chemical detoxification of the body. The antioxidant effect of acetylcysteine increases the protection of cells against the damaging effects of free radical oxidation, which is characteristic of an intense inflammatory reaction. With prophylactic use of acetylcysteine, a decrease in the frequency and severity of exacerbations in patients with chronic bronchitis and cystic fibrosis has been observed.
Indications
Respiratory diseases and conditions associated with the formation of viscous and mucopurulent sputum: acute and chronic bronchitis, tracheitis due to bacterial and / or viral infections, pneumonia, bronchiectasis, bronchial asthma, atelectasis due to blockage of bronchi by mucous plug, sinusitis (to ease the discharge of secretions ), cystic fibrosis (as part of combination therapy). Removal of viscous secretions from the respiratory tract in post-traumatic and postoperative conditions. Paracetamol overdose.
Use during pregnancy and lactation
Overdose
Side effects
The simultaneous use of acetylcysteine with antitussives can increase the stagnation of sputum due to suppression of the cough reflex. When used simultaneously with antibiotics (including tetracycline, ampicillin, amphotericin B), their interaction with the thiol group of acetylcysteine is possible. Acetylcysteine reduces the hepatotoxic effect of paracetamol.
special instructions
The simultaneous use of acetylcysteine with antitussives can increase the stagnation of sputum due to the suppression of the cough reflex. When used simultaneously with antibiotics (including tetracycline, ampicillin, amphotericin B), their interaction with the thiol group of acetylcysteine is possible. Acetylcysteine reduces the hepatotoxic effect of paracetamol.