Capsule structure 500 mg 60 pcs
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Active ingredients
Chondroitin sulfate
Release form
Capsules
Composition
Active ingredient: chondroitin sulfate sodium 500 mg. Excipients: Talc - 10 mg. Capsule shell composition: indigo carmine, titanium dioxide, gelatin. Size no0
Pharmacological effect
Anti-inflammatory, chondroprotective. Affects metabolic processes in hyaline and fibrous cartilage, reduces degenerative changes in the cartilage tissue of the joints, stimulates the biosynthesis of glycosaminoglycans. It slows down bone resorption and reduces calcium loss, accelerates bone repair processes. In the treatment with Struktum, the pain decreases and the mobility of the affected joints improves. The therapeutic effect persists for a long time after the end of the course of treatment.
Pharmacokinetics
More than 70% of chondroitin sulfate is absorbed in the digestive tract. Bioavailability of the drug is 13%. With a single ingestion of the average therapeutic dose of Cmax in plasma is noted in 3-4 hours, in the synovial fluid in 4-5 hours. The drug absorbed in the gastrointestinal tract accumulates in the synovial fluid. Excreted by the kidneys
Indications
Osteoarthritis; intervertebral osteochondrosis
Contraindications
Hypersensitivity to the components of the drug; - children's age up to 15 years (due to the lack of accurate data). Use during pregnancy and lactation
Precautionary measures
With a single dose of the drug Struktum and the use of fibrinolitikov, antiplatelet agents and indirect anticoagulants there is a possibility of increasing the effect of the latter. In this case, more frequent and careful monitoring of blood coagulation indices is necessary. Studies on the interaction of the drug with dietary supplements have not been carried out, but it is advisable to carefully use Struktum with drugs containing calcium and side substances that promote its absorption (such as vitamin D3 )
Use during pregnancy and lactation
Structum is not recommended to appoint during pregnancy and lactation (breastfeeding) due to the lack of sufficient clinical data
Dosage and administration
Capsules are taken orally, drinking water. For adults and adolescents aged 15 years and older, the drug is prescribed in a dose of 1 g / day - 2 capsules each 250 mg or 1 capsule 500 mg 2 times / day. The recommended duration of the initial course of treatment is 6 months.The therapeutic effect of the drug lasts for 3-5 months after its cancellation, depending on the location and stage of the disease. If necessary, it is possible to conduct repeated courses of treatment, the duration of which the doctor determines individually
Side effects
On the part of the digestive system: rarely - nausea, vomiting. Allergic reactions: rarely - urticaria, erythema, pruritus
Overdose
Symptoms: rarely - nausea, vomiting, diarrhea, with prolonged use in excessively high doses (more than 3 g / day) hemorrhagic rashes are possible. Treatment: symptomatic therapy
Interaction with other drugs
With simultaneous use with the drug Struktum may enhance the effect of indirect anticoagulants, antiplatelet agents and fibrinolytics
special instructions
Be wary of prescribing the drug for bleeding or bleeding tendency.