Cromohexal eye drops 2% 10ml
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Active ingredients
Cromoglicic acid
Release form
Drops
Composition
Active ingredient: Cromoglicic acid (cromoglicic acid) Active ingredient concentration (%): 2%
Pharmacological effect
Antiallergic drug. Mast cell membrane stabilizer. It has a membrane stabilizing effect, blocks the entry of calcium ions into the mast cell, preventing its degranulation and the release of histamine, bradykinin, prostaglandins, leukotrienes (including slow-reacting substance) and other biologically active substances. The drug is most effective as means of prevention. A noticeable clinical effect occurs within a few days or weeks after administration.
Pharmacokinetics
Absorption and distribution Absorption through the mucous membrane of the eye is negligible. Systemic bioavailability - less than 0.03%. Communication with plasma proteins - 65%. Metabolism and excretion is not metabolized. Excreted by the kidneys and through the intestine in unchanged form (approximately in equal amounts within 24 hours after application). T1 / 2 - 5-10 minutes.
Indications
The drug is prescribed to elderly people with disorders of cerebral circulation, accompanied by: a disorder of attention and / or memory, a violation of intellectual abilities, anxiety, fear, dizziness, noise in the ears, sleep disorders. Appointed also in cases of circulatory disorders of the lower extremities.
Contraindications
Children's age up to 2 years; Hypersensitivity to sodium cromoglycate or to any other component of the drug.
Precautionary measures
Contraindicated in children under 2 years old, with caution - children under 4 years old.
Use during pregnancy and lactation
Caution should be used drug Kromogeksal during pregnancy and lactation.
Dosage and administration
Adults and children over the age of 2 years old are instilled 1-2 drops in each conjunctival sac 4 times / day with an interval of 4-6 hours. If necessary, the dose can be increased to 6-8 instillations. After reaching the therapeutic effect, the frequency of the drug can be reduced and use Kromoheksal only in contact with allergens (house dust, fungal spores, pollen).
Side effects
On the part of the organ of vision: impaired visual perception, burning in the eye, conjunctival edema, foreign body sensation, dry eye, tearing, meybomit (barley); superficial damage to the corneal epithelium.
Overdose
Data overdose of the drug is not available.
Interaction with other drugs
So far, no interaction with other drugs has been identified.
special instructions
The use of the drug Kromoheksal reduces the need for the use of ophthalmic drugs containing glucocorticoids. When using Kromoheksal drops, due to the content of benzalkonium chloride, you should avoid wearing soft contact lenses; hard contact lenses must be removed 15 minutes before instillation and put on after 15 minutes. The bottle must be closed after each use. You should not touch the eye with a pipette tip. Impact on the ability to drive vehicles and control mechanisms. During the period of treatment, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and psychomotor speed.