Iodomarin100 pills 100 mcg 100 pcs
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Active ingredients
Potassium iodide
Release form
Pills
Composition
1 tablet contains: Active ingredient: potassium iodide 131 mcg, which corresponds to an iodine content of 100 mcg. Auxiliary substances: lactose monohydrate - 75.119 mg, magnesium basic carbonate - 28.25 mg, gelatin - 4 mg, sodium carboxymethyl starch (type A) - 4.75 mg, colloidal silicon dioxide - 1.75 mg, magnesium stearate - 1 mg.
Pharmacological effect
Iodine preparation for the treatment and prevention of diseases of the thyroid gland. Iodine is a vital trace element necessary for the normal functioning of the thyroid gland. Thyroid hormones perform many vital functions, including regulate the metabolism of proteins, fats, carbohydrates and energy in the body, the activity of the brain, nervous and cardiovascular systems, the genital and mammary glands, as well as the growth and development of the child. The use of the drug Jodomarin; compensates for iodine deficiency in the body, preventing the development of iodine deficiency disorders, contributes to the normalization of thyroid function, which is especially important for children and adolescents, as well as during pregnancy and lactation.
Pharmacokinetics
Data on the pharmacokinetics of the drug Iodomarin; not provided.
Indications
- Prevention of endemic goiter (especially in children, adolescents, women during pregnancy and breastfeeding); Prevention of goiter recurrence after surgical removal or after termination of drug therapy with thyroid hormone drugs; - Treatment of diffuse euthyroid goiter caused by iodine deficiency children, adolescents and in adults under 40 years of age.
Contraindications
- hyperthyroidism; - toxic thyroid adenoma, nodular goiter when used in doses of more than 300 mcg / day (except for the period of preoperative iodine therapy to block thyroid function); - herpetiformis (senile) During dermatitis; - hypersensitivity to iodine. should be used for hypothyroidism, except in cases where the development of the latter is caused by a pronounced iodine deficiency. Avoid prescribing the drug during therapy with radioactive iodine, the presence or suspicion of thyroid cancer PS.
Use during pregnancy and lactation
During pregnancy and lactation, the need for iodine increases, so the use of the drug Iodomarin is especially important; in sufficient doses (200 mcg / day) to ensure adequate iodine intake in the body. Use of the drug Iodomarin; during pregnancy and lactation (breastfeeding) is possible only in recommended doses, since the active substance passes through the placenta and is excreted in breast milk.
Dosage and administration
Prevention of endemic goiter Newborns and children under the age of 12 1 / 2-1 tab. drug iodomarin; 100 or 1/2 tab. drug iodomarin; 200 per day (which corresponds to 50-100 mcg of iodine). Children over 12 years old and adults 1-2 tab. drug iodomarin; 100 or 1 / 2-1 tab. drug iodomarin; 200 per day (which corresponds to 100–200 mcg of iodine). During pregnancy and lactation 2 tab. drug iodomarin; 100 or 1 tab. drug iodomarin; 200 per day (which corresponds to 200 mcg of iodine). Prevention of goiter recurrence tab. drug iodomarin; 100 or 1 / 2-1 tab. drug iodomarin; 200 per day (which corresponds to 100–200 mcg of iodine). Treatment of euthyroid goiter Newborn and children aged 1 to 18 years 1–2 tab. drug iodomarin; 100 or 1 / 2-1 tab. drug iodomarin; 200 per day (which corresponds to 100–200 mcg of iodine). Adults under 40 3–5 tab. drug iodomarin; 100 per day or 11 / 2-21 / 2 tab. drug iodomarin; 200 per day (which corresponds to 300-500 mcg of iodine). The drug is taken after a meal, drinking a sufficient amount of liquid. When used in children, it is recommended to pre-dissolve the drug in milk or juice. Preventive intake is carried out for several years, if indicated, for life. For the treatment of goiter in newborns, on average, 2-4 weeks is enough; children, adolescents and adults usually require 6-12 months, long-term administration is possible. The duration of treatment is determined by the attending physician.
Side effects
With the prophylactic use of the drug Iodomarin; in patients of any age, side effects are usually not observed. From the endocrine system: when using the drug in a dose of more than 150 mcg of iodine / day, latent hyperthyroidism can turn into manifest form; with the use of the drug in a dose exceeding 300 mcg iodine / day, the development of iodine-induced thyrotoxicosis is possible (especially in elderly patients,suffering from goiter for a long time, in the presence of nodular goiter or diffuse toxic goiter in some cases - angioedema, exfoliative dermatitis.
Overdose
Symptoms: staining of mucous membranes in brown color, reflex vomiting (in the presence of food starch containing components vomit become blue in color), abdominal pain and diarrhea (possibly melena). In severe cases, dehydration and shock may develop. In rare cases, stenosis of the esophagus, the phenomenon of iodism was observed. Treatment: for acute intoxication, drug withdrawal, gastric lavage with a solution of starch, protein or 5% sodium thiosulfate solution before removing all traces of iodine; with chronic intoxication - the abolition of the drug. Symptomatic therapy of impaired water balance, electrolyte balance, antishock therapy. When treating iodine-induced hypothyroidism - drug withdrawal, normalization of metabolism using thyroid hormones. When treating iodine-induced thyrotoxicosis - no treatment is required for mild forms, for severe forms thyreostatic therapy (the effect of which is always delayed). In severe cases (thyrotoxic crisis), intensive therapy, plasma exchange or thyroidectomy are necessary.
Interaction with other drugs
Iodine deficiency increases, and excess iodine reduces the effectiveness of therapy for hyperthyroidism with thyrostatic agents (before or during treatment for hyperthyroidism, it is recommended to avoid any use of iodine, if possible). On the other hand, thyreostatics inhibit the transfer of iodine to an organic compound in the thyroid gland and, thus, can cause goiter formation. Simultaneous treatment with high doses of iodine and preparations of lithium salts can contribute to goiter and hypothyroidism. High doses of the drug in combination with potassium-sparing diuretics can lead to hyperkalemia.
special instructions
Impact on the ability to drive vehicles and control mechanisms Iodomarin; does not affect the ability to drive vehicles and other potentially dangerous activities.