More info
Active ingredients
Dioxomethyltetrahydropyrimidine + Chloramphenicol
Release form
Ointment
Composition
Active ingredient: Dioxomethyltetrahydropyrimidine + Chloramphenicol (Dioxomethyltetrahydropyrimidine + Chloramphenicol) Active ingredient concentration (mg): Dioxomethyltetrahydropyrimidine (methyluracil) - 40 mg, chloramphenicol - 7 mg
Pharmacological effect
Combined preparation for local use, has anti-inflammatory (dehydrating) and antimicrobial effect, is active against gram-positive and gram-negative microorganisms (staphylococcus, pseudomonas and intestinal sticks). Easily penetrates deep into tissues without damaging biological membranes, stimulates regeneration processes. In the presence of pus and necrotic masses, the antibacterial effect is maintained.
Pharmacokinetics
Data on the pharmacokinetics of the drug is not provided.
Indications
Purulent wounds (including those infected with mixed microflora) in the first (purulent-necrotic) phase of the wound process.
Contraindications
Hypersensitivity to the drug; children up to 1 year old (in newborns, the biotransformation of chloramphenicol is slower than in adults).
Precautionary measures
Do not exceed recommended doses.
Use during pregnancy and lactation
Use during pregnancy is possible only if the benefit to the mother exceeds the risk to the fetus. During lactation, you should either discontinue use of the drug or breastfeed.
Dosage and administration
Locally. The drug is impregnated with sterile gauze wipes, which loosely fill the wound. It is possible to introduce into the purulent cavities through the catheter (drainage tube) with a syringe. In this case, the ointment is preheated to 35-36 ° C. Ligation produced daily, to complete cleansing of the wound from the purulent-necrotic masses.
Side effects
Allergic reactions (skin rash).
Overdose
Cases of drug overdose Levomekol ointment were not reported.
Interaction with other drugs
Cases of interaction or incompatibility with other drugs are not described.
special instructions
Impact on the ability to drive motor vehicles and control mechanismsHe does not have.