Lincomycin hydrochloride injection solution ampoules 30% 1ml N10
Condition: New product
990 Items
Rating:
Be the first to write a review!
More info
Active ingredients
Lincomycin
Release form
Solution
Composition
In 1 ml solution for injection contains: lincomycin hydrochloride 0.3 g
Indications
Lincomycin hydrochloride, a solution for intravenous and intramuscular administration, is indicated for the treatment of severe infections caused by susceptible strains of microorganisms (see the Pharmacological Properties section). Its use should be reserved for patients who cannot use penicillin or are allergic to penicillin. Because of the risk of pseudomembranous colitis associated with lincomycin, when prescribing lincomycin, the severity of infection and the possibility of using less toxic drugs (eg, erythromycin) should be taken into account. It is possible to conduct surgical procedures in combination with antimicrobial therapy. It is possible to use lincomycin with other antimicrobial drugs simultaneously. pokazaniy.Linkomitsin presence should not be used in bacterial infections mild degree or viral zabolevaniyah.Chtoby reduce the development of drug-resistant bacteria and maintain the effectiveness of lincomycin and other antibacterials lincomycin should only be used to treat or prevent infections with proven or suspected sensitive microorganism. When data are available on the type and sensitivity of the pathogen, they are used to select or change antibiotic therapy. In the absence of such data, local information on the epidemiology and sensitivity of microorganisms can be used for empirical treatment.
Contraindications
Hypersensitivity to lincomycin, clindamycin and auxiliary components of the drug, pregnancy (except when necessary for health reasons), lactation, early infancy (up to 1 month). C caution: severe hepatic and / or renal failure, fungal diseases of the skin, oral mucosa, vagina. myasthenia gravis (for parenteral administration).
Dosage and administration
Adults: Intramuscularly - 600 mg (2 ml) every 24 hours. For more severe infections, 600 mg (2 ml) every 12 hours or more. Intravenous - from 600 mg (2 ml) to 1000 mg every 8-12 hours.With more severe course of the dose may be increased. In life-threatening situations, it is possible to administer up to 8 grams per day. Children over 1 month old: intramuscularly at a dose of 10 mg / kg body weight every 24 hours. With a more severe course - 10 mg / kg body weight every 12 hours or more. Intravenous - from 10 to 20 mg / kg / day, depending on the severity of the infection. Can be used in divided doses, as described above for adults.
Side effects
On the part of the digestive system, nausea, vomiting, diarrhea, epigastric pain, abdominal pain, glossitis, stomatitis, transient hyperbilirubinemia, increased activity of hepatic transaminases, with prolonged use - gastrointestinal candidiasis, pseudomembranous colitis. , neutropenia. rarely agranulocytosis, aplastic anemia, pancytopenia. Allergic reactions of urticaria, skin rash, exfoliative and bullous dermatitis, Quincke edema, anaphylactic shock, erythema multiforme, Stevens-Johnson syndrome, serous, pruritus anus, multiforme erythema, serous, itchy, anus, in the anus, there is no reason that the object is already in the anus. - renal dysfunction (azotemia, oliguria and / or proteinuria). On the part of the sensory organs in some cases - tinnitus and dizziness. Local reactions are pain together with intramuscular administration. when administered intravenously, phlebitis. With rapid intravenous administration, a decrease in blood pressure, dizziness, general weakness, relaxation of skeletal muscles. Other vaginitis.