Phosphogliv forte capsules N50
Condition: New product
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Active ingredients
Glycyrrhizic acid + Phospholipids
Release form
Capsules
Composition
1 capsule contains: Active substance: phospholipids (lipid PPL-400) 400 mg, in terms of the main component - phosphatidylcholine 73-79% 300 mg Supplemental substances: sodium glycyrrhizinate (trisodium salt of glycyrrhizic acid) 65 mg
Pharmacological effect
Combined preparation. It exerts membrane stabilizing, hepatoprotective and antiviral effects. Phosphatidylcholine (the main component of phospholipids) is the main structural element of cellular and intracellular membranes, is able to restore their structure and function when damaged, providing a cytoprotective effect. other active substances, restores liver detoxification function, inhibits the formation of connect Flax tissue, reducing the risk of fibrosis and cirrhosis. Glycyrate (glycyrrhizic acid and salts) has an anti-inflammatory effect, inhibits viral reproduction in the liver and other organs by stimulating the production of interferons, increasing phagocytosis, and increasing the activity of natural killer cells. It has a hepatoprotective effect due to antioxidant and membrane stabilizing activity. Potentiates the action of endogenous glucocorticosteroids, providing an anti-inflammatory and antiallergic effect in non-infectious lesions of the liver. In skin lesions due to the membrane-stabilizing and anti-inflammatory action of the components limits the spread of the process and contributes to the regression of the disease.
Pharmacokinetics
The components of the drug are well absorbed in the intestine, both as a whole molecule, and bioactive products of their hydrolysis (unsaturated fatty acids, choline, glycyrrtic acid), which, after being absorbed through the intestinal walls, easily penetrate the liver, lungs, skin and other organs.
Indications
- viral hepatitis (acute and chronic); - fatty degeneration of the liver (hepatosis); - medicinal, alcoholic, toxic liver damage; - liver cirrhosis; - intoxication; - psoriasis; - neurodermatitis; - eczema.
Contraindications
- pregnancy; - lactation period; - children's age up to 12 years; - hypersensitivity to the drug components.
Use during pregnancy and lactation
The drug is contraindicated for use during pregnancy and lactation.
Dosage and administration
The drug is taken orally during meals. Capsules should be taken with a small amount of liquid. Adults should be given 1-2 capsules each. 3 times / day, children over 12 years old - 1 caps. 3 times / day
Side effects
Dermatological reactions: skin rash, which disappears after discontinuation of the drug (with increased individual sensitivity). Rarely, when the daily doses are exceeded, sodium and fluid retention may occur, which is manifested by peripheral edema and increased blood pressure, hypokalemia.
Overdose
Cases of drug overdose Phosphogliv Forte is not marked.
Interaction with other drugs
Drug interaction of the drug Phosphogliv Forte is not described.
special instructions
When sodium and fluid retention and hypokalemia appear, depending on their severity, it is necessary to reduce the dose of the drug and / or prescribe spironolactone at 50-100 mg / day.