Sinuforte lyophilisate for solutionnasal 50mg
Condition: New product
996 Items
Rating:
Be the first to write a review!
More info
Active ingredients
Lyophilisate juice and extract of fresh tubers of European cyclamen
Release form
Powder
Composition
Active ingredient: lyophilized juice and extract of European cyclamen tubers; fresh active ingredient concentration (mg): 50 mg
Pharmacological effect
The drug of plant origin for the treatment of inflammatory diseases of the paranasal sinuses (SNPs) and the nasal cavity. The drug affects the sensory receptors of the trigeminal nerve in the region of the middle nasal passage and causes reflex secretion in the nasal mucosa and SNPs. Stimulated hypersecretion is accompanied by a change in the rheological properties of the secret and the normalization of its viscosity. Reflex hypersecretion in combination with the anti-edema effect of the drug leads to the evacuation of the secret from the sinuses into the nasopharynx and provides physiological drainage of all the sinuses simultaneously. The drug helps to restore mucociliary transport in the nasal cavity and SNPs by increasing the presence of the liquid part of the secretion in the surface layer of mucus. Sinuforte enhances blood microcirculation in the nasal mucosa and SNPs. This is due to the fact that parasympathetic stimulation, which activates secretion, also causes vasodilation of the vessels supplying the glands. Enhanced reflex secretion in the form of serous-mucosal secretions is detected in a few minutes and can last from 30 to 120 minutes depending on the individual characteristics of the organism.
Pharmacokinetics
The action of the drug Sinuforte due to the cumulative effects of the components of cyclamen, the most studied of which are triterpenic saponins. It is not possible to conduct kinetic studies, since all the components together cannot be traced using markers or bioassays. For the same reason, it is impossible to detect metabolites of the drug.
Indications
complex therapy of acute and chronic sinusitis: sinusitis, frontal sinusitis, ethmoiditis and sphenoiditis (in the case of purulent sinusitis, occurring with symptoms of generalization of infection and / or orbital complications, Sinuforte should be used only in combination with antibiotics).With an uncomplicated course of the disease, it is possible to use the drug as a means of monotherapy under the supervision of a physician, complex therapy of rhinosinusitis, accompanied by exudative otitis media; the period of early postoperative rehabilitation after endoscopic surgical interventions on the paranasal sinuses.
Contraindications
hypersensitivity to the components of the drug; polypous rhinosinusitis; cysts of the paranasal sinuses; allergic rhinosinusopathies; allergic reactions (delayed and immediate); arterial hypertension II – III degree; pregnancy (safety of use during this period); lactation the period has not been studied); children's age up to 5 years (use in children under 5 years old has not been studied).
Use during pregnancy and lactation
Contraindicated in pregnancy and lactation.
Dosage and administration
Intranasal, adults and children over 5 years old. Sequence of actions when using the drug. Unscrew the cap from the bottle with the drug and remove the cork. Open the solvent bottle, break off the upper part. Fully pour the solvent contents into the bottle with the drug. dissolving the drug. Remove the protective cap from the dispenser-dispenser. Produce 2-3 test sprays in the air. In an upright head position, dispense the dispenser in each nasal passage, holding breathing and spraying at the touch of a button. Each time you press the dispenser sprays 0.13 ml (2-3 drops) of the drug, which is about 1.3 mg of the drug (single dose). The preparation prepared by the above method is administered once a day by a single spray in each nasal passage. The drug is recommended to be used daily, if necessary, its use is allowed every other day. The duration of one course of treatment is 12–16 days with the administration of the drug every other day or 6–8 days for daily use.
Side effects
You may experience a feeling of mild or moderate burning in the nasal cavity, saliva and / or tearing in response to irritation of the sensory receptors of the trigeminal nerve. In some cases, you may experience facial flushing, a short headache in the frontal region or a pale pink colored discharge from the nose as a result of capillary diapedesis.The above short-term physiological reactions confirm the reflex mechanism of the drug's action and do not require cessation of treatment. Allergic reactions are possible (including skin rash, shortness of breath, etc.). In these cases, it is recommended to stop taking the drug and consult a specialist.
Overdose
Currently, cases of drug overdose Sinuforte were reported. Exceeding a single dose does not lead to an increase in the therapeutic effect and may cause a strong burning sensation and pain in the nasopharynx. If symptoms of overdose appear, symptomatic therapy is necessary: wash the nasal cavity, rinse the throat with warm water and apply antihistamines.
Interaction with other drugs
It is necessary to refrain from prior administration, as well as the simultaneous use of local anesthetics and / or local decongestants due to a possible violation of the mechanism of action of the drug Sinuforte. If necessary, the combination of Sinuforte's drug with antibacterial drugs is possible and acceptable. Interactions with other drugs have not yet been studied .
special instructions
During the postoperative rehabilitation period after endoscopic interventions, Sinuforte is used on the second day to cleanse (reorganize) the paranasal sinuses and the nasal cavity and reduce mucosal edema. When using, avoid contact with Sinuforte eyes due to the presence of an irritating effect of the drug on the mucous membrane of the eye and the possible development of the phenomena of acute conjunctivitis. It is recommended to hold the breath during the administration of the drug. Directly spraying the drug should be carried out with one touch when the head is upright. -torinolaryngologist.