Troxevasin capsules 300 mg 50 pcs
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Active ingredients
Troxerutin
Release form
Capsules
Composition
Active ingredient: Troxerutin (Troxerutin) Active ingredient concentration (mg): 300
Pharmacological effect
Angioprotective drug, acts primarily on the capillaries and veins. It reduces the pores between endothelial cells by modifying the fibrous matrix located between the cells of the endothelium. inhibits aggregation and increases the degree of red blood cell deformability; It has an anti-inflammatory effect. In chronic venous insufficiency, troxevasin reduces the severity of swelling, pain, seizures, trophic disorders, varicose ulcers. relieves the symptoms associated with hemorrhoids - pain, itching and bleeding. Thanks to its beneficial effects on the permeability and resistance of the capillary walls, troxevasin helps to slow down the development of diabetic retinopathy. in addition, its effect on the rheological properties of blood contributes to the prevention of microthrombosis of retinal vessels.
Pharmacokinetics
Absorption After oral absorption is about 10-15%. Cmax in plasma is reached on average 2 hours after administration, the therapeutic plasma level is maintained for 8 hours. Metabolism and excretion Metabolized in the liver. Partially excreted unchanged in the urine (20-22%) and with bile (60-70%).
Indications
Varicose veins; Chronic venous insufficiency with symptoms such as: swelling and pain in the legs; feeling of heaviness, fatigue, tired legs; spider veins and spider veins, convulsions, paresthesias; Thrombophlebitis; Periphlebitis; Varicose dermatitis; Traumatic pain and swelling (bruises, sprains, injuries).
Contraindications
Hypersensitivity to rutoside or to other components of the drug. Pregnancy (I trimester). Peptic ulcer and duodenal ulcer, chronic gastritis in the acute phase. With care: it is necessary to apply (long-term use) at a renal failure.
Precautionary measures
The drug should be kept out of the reach of children, dry, protected from light, at a temperature not exceeding 25 ° C.
Use during pregnancy and lactation
The use of the drug Troxevasin in the first trimester of pregnancy is contraindicated. In the second and third trimesters and during lactation (breastfeeding) use of the drug is possible when the expected benefit of therapy for the mother outweighs the potential risk to the fetus or infant.
Dosage and administration
Inside at the beginning of treatment, 1 capsule is prescribed 2 times a day (in the morning and evening), and during maintenance therapy, 1 capsule per day for 3-4 weeks or more. When retinopathy drug is prescribed 1-2 capsules 3 times a day. Capsules should be taken with meals.
Side effects
Possible: allergic reactions, erosive and ulcerative lesions of the gastrointestinal tract, headache.
Overdose
Symptoms: agitation, nausea, headache, hot flashes to the face. Treatment: gastric lavage, taking activated charcoal, if necessary - conducting symptomatic therapy.
Interaction with other drugs
The effect of the drug is enhanced while taking ascorbic acid.
special instructions
If during the period of use of the drug the severity of symptoms of the disease does not decrease, you should consult with your doctor. Pediatric use influences on motor and mental reactions, does not interfere with the management of vehicles and work with mechanisms.