Valparin XP coated pills prolonged 300mg N100
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Description
Venozol is an ideal preparation for a modern woman caring for the beauty of her legs. Venozol is a dietary supplement containing a complex of active substances, which includes diosmin, hesperidin, dihydroquercetin, extract of the hazelnut leaf, horse chestnut fruit extract, calcium carbonate. Such a multicomponent composition allows to have a multifactorial therapeutic effect on all parts of the vascular venous pathology and the pathology of the lymphatic system. The drug causes an increase in venous tone, normalization of venous outflow and microcirculation in the lower extremities, normalization of lymphatic drainage. When taken, pain, heaviness, edema and night cramps in the lower extremities disappear, skin color in the lower extremities normalizes, trophic ulcers in the lower legs and heals heal stop, the sizes of varicose nodes decrease, vascular "asterisks" and "reticulums" disappear.
Active ingredients
Valproic acid
Release form
Pills
Composition
Diosmin 300 mg, chestnut extract 50 mg, hesperidin 30 mg, hazel extract 17 mg, dihydroquercetin 3 mg.
Pharmacological effect
Anticonvulsant drug. Sodium valproate increases the content of gamma aminobutyric acid (GABA) in the brain, which accordingly increases the content of GABA in postsynaptic neurons. In addition, sodium valproate affects the transfer of potassium ions through the membranes of neurons. As a result, the development as well as the spread of epileptic excitation along neurons is suppressed .; Sodium valproate has anticonvulsant activity in various types of epilepsy in humans. The drug does not have a pronounced hypnotic and sedative effects, and also has no inhibitory effect on the respiratory center. Sodium valproate does not have a negative effect on blood pressure, heart rate, kidney function and body temperature.
Pharmacokinetics
Absorption; After ingestion of pills with controlled release of Cmax in plasma is achieved within 2-8 hours. The bioavailability of the drug is about 100%; Therapeutic efficacy is manifested when the concentration of valproic acid in the blood plasma is 40-100 mg / l. At the same time, the pharmacological and therapeutic effects of this drug with controlled release do not always depend on its concentration in the plasma .; Distribution; Binding to plasma proteins is 80-90%; Vd is 0.2 l / kg .; Metabolism and excretion; Metabolized in the liver and excreted in the urine. Presystemic metabolism is not observed.T1 / 2 is approximately 8-20 hours; Pharmacokinetics in special clinical situations; In children, T1 / 2 decreases.
Indications
- Varicose veins of the lower extremities, swelling, pain, convulsions, heaviness in the lower extremities, trophic disorders in the lower extremities (cyanosis, cyanosis, trophic ulcers), - Hemorrhoids, - Thrombophlebitis, - Preoperative preparation, postoperative treatment of varicose veins, presence of vascular "asterisks" and "reticulums" on the skin of the lower extremities, varicocele, impaired venous outflow from the cranial cavity in hypertensive syndrome in neurological practice.
Contraindications
- severe dysfunction of the pancreas; - acute or chronic hepatitis, cases of active hepatitis in the family history (primarily of medicinal genesis); - porphyria; - thrombocytopenia; - pregnancy; - lactation (breastfeeding); - children's age up to 3 years; - Hypersensitivity to valproic acid and other components of the drug.
Precautionary measures
Before use, it is recommended to consult with a specialist.
Use during pregnancy and lactation
Contraindicated in pregnancy and lactation.
Dosage and administration
Adults and children over 14 years old 1 capsule 1-2 times a day with meals (according to the instructions) 6-8 weeks.
Side effects
Allergic reactions
special instructions
Contraindicated in case of individual intolerance to the components, pregnancy and breastfeeding, children under 14 years old.