Buy Vinpocetine Izvarino tablets 10mg N30

Vinpocetine Izvarino pills 10mg N30

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Active ingredients

Vinpocetine

Release form

Pills

Composition

1 tablet contains: Active ingredient: Vinpocetine 10 mg. Excipients: Magnesium stearate, colloidal silicon dioxide, talc, lactose monohydrate, corn starch.

Pharmacological effect

A means of improving cerebral circulation and brain metabolism. Inhibits phosphodiesterase activity, which contributes to the accumulation of cAMP in tissues. It has a vasodilating effect mainly on the vessels of the brain, which is caused by direct myotropic antispasmodic action. Systemic blood pressure drops slightly. It improves blood circulation and microcirculation in the brain tissues, reduces platelet aggregation, and contributes to the normalization of the rheological properties of blood. It improves the tolerance of hypoxia by brain cells, facilitating the transport of oxygen to tissues due to a decrease in the red blood cell affinity for it, enhancing the absorption and metabolism of glucose. Increases the content of catecholamines in brain tissue.

Pharmacokinetics

When ingestion is rapidly absorbed from the gastrointestinal tract. Cmax in plasma is reached in approximately 1 hour. When administered parenterally, Vd is 5.3 L / kg. T1 / 2 is about 5 h.

Indications

Acute (if parenteral administration is impossible) and chronic forms of cerebral circulatory insufficiency (including acute and residual stages of stroke, transient ischemic attacks, encephalopathy, dementia after cerebral circulatory disorders). atherosclerosis, angiospasm, thrombosis). degenerative changes in macula caused by atherosclerosis or angiospasm. secondary glaucoma (due to vascular obturation). Age-related vascular or toxic (medical) hearing loss, Meniere's disease, dizziness of labyrinth origin. Vegetative manifestations of menopausal syndrome.

Contraindications

Severe cardiac arrhythmias. IBS (severe). Acute stage of hemorrhagic stroke. Renal failure. Liver failure. Children's age up to 14 years. Pregnancy. Lactation (breastfeeding). Hypersensitivity to the drug.

Precautionary measures

Since the cardiovascular system: transient arterial hypertension, tachycardia; rarely - beats, an increase in time of excitation of the ventricles.

Use during pregnancy and lactation

Contraindicated for use in pregnancy. Data on the safety of use during lactation are not available.

Dosage and administration

Inside: 5-10 mg three times a day.

Side effects

On the part of the cardiovascular system, a decrease in blood pressure, tachycardia, extrasystole, slowing of intraventricular conduction.

Interaction with other drugs

When applied simultaneously with warfarin, a small decrease in the anticoagulant effect of warfarin has been reported. With simultaneous parenteral administration of vinpocetine and heparin, there may be an increased risk of bleeding.

special instructions

With caution used internally for arrhythmias, angina, with unstable blood pressure and low vascular tone. Parenteral, as a rule, is used in acute cases to improve the clinical picture, then move to ingestion. In chronic diseases, Vinpocetine is taken orally. In hemorrhagic cerebral stroke, parenteral administration of vinpocetine is allowed only after the reduction of acute events (usually 5-7 days).

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