Don injection solution 400mg 2ml ampoules 2ml N6
Condition: New product
1000 Items
Rating:
Be the first to write a review!
More info
Active ingredients
Glucosamine Sulfate
Release form
Solution
Composition
Active ingredient: Glucosamine (Glucosamine). Concentration of the active substance (mg): 400
Pharmacological effect
Dona - has anti-inflammatory and analgesic effect, fills up the endogenous deficiency of glucosamine, stimulates the synthesis of proteoglycans and hyaluronic acid of synovial fluid; increases the permeability of the articular capsule, restores the enzymatic processes in the cells of the synovial membrane and articular cartilage. It promotes sulfur fixation during the synthesis of chondroitin sulfuric acid, facilitates the normal deposition of calcium in bone tissue, inhibits the development of degenerative processes in the joints, restores their function, reducing joint pain.
Pharmacokinetics
When administered intramuscularly, the bioavailability of 95%, quickly spreads in the tissues, T1 / 2 about 60 hours, mainly excreted by the kidneys.
Indications
Primary and secondary osteoarthritis of various localization, osteochandrosis. It is widely used in rheumatological, traumatological, neurological and sports practice.
Contraindications
Individual hypersensitivity to glucosamine, lidocaine hydrochloride and other components of the drug. Due to the presence of lidocaine in the composition of the product, it is contraindicated in patients with impaired cardiac conduction and acute heart failure, history of epileptiform convulsions, severe disorders of the liver and kidneys; during pregnancy and lactation, as well as in children up to 12 years.
Precautionary measures
Do not exceed the recommended dose. With care: patients with chronic heart failure, arterial hypotension. Caution should be exercised in patients with allergies to seafood (shrimp, shellfish).
Use during pregnancy and lactation
Contraindicated during pregnancy and lactation.
Dosage and administration
Before intramuscular injection mix the contents of the ampoule (drug) with the attached solvent. The prepared solution is administered in 3 ml 3 times a week for 4–6 weeks. Injections of the drug are effectively combined with the simultaneous or alternate intake of powders.With the combined treatment with injections and powders, the dosages and the route of administration and doses remain unchanged.
Side effects
Tolerability is good. In some cases, possible: flatulence, diarrhea, constipation, allergic reactions - urticaria, itching. Due to the content in the drug lidocaine may be: nausea, vomiting, drowsiness, diplopia, headache, dizziness, numbness of the tongue and oral mucosa, tremor, euphoria, disorientation, impaired cardiac conduction.
Overdose
Cases of overdose are not marked.
special instructions
When using the drug in patients with impaired glucose tolerance, with severe hepatic and renal insufficiency, medical supervision is necessary.