Floxal ophthalmic ointment 0.3% 3 g
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Active ingredients
Ofloxacin
Release form
Ointment
Composition
On 1 ml: ofloxacin 3 mg. Excipients: liquid paraffin - 100 mg, wool fat - 50 mg, white petrolatum - 847 mg.
Pharmacological effect
Antimicrobial broad-spectrum drug from the group of fluoroquinolones for local use in ophthalmology. The bactericidal action of ofloxacin is associated with the blockade of the DNA gyrase enzyme in bacterial cells. It is highly active against most Gram-negative microorganisms: Esherichia coli, Salmonella spp., Proteus spp., Morganella morganii, Shigella spp., Klebsiella spp., Ibrahimla morganella morganii, Shigella spp., Ibrahim morph, etc. , Citrobacter spp., Yersinia spp., Providencia spp., Haemophilus influenzae, Neowseria gonorrhoeae, Neisseria gonorrhoeae, Neisseria meningitidis, Mycoplasma spp., Legionella pneumophila, Acinetobacter spp., Chlamydia spp. Spp. Moderately sensitive to ofloxacin Enterococcus faecalis, Streptococcus pneumoniae, Pseudomonas spp. To ofloxacin microorganisms producing β-lactamazu are sensitive. Anaerobic bacteria are insensitive to the preparation (except for Bacteroides urealyticus).
Pharmacokinetics
When applied topically, a therapeutic concentration of the drug in the eye tissue is achieved.
Indications
Infectious and inflammatory diseases of the anterior part of the eye caused by microorganisms that are sensitive to ofloxacin: - blepharitis; - barley; - conjunctivitis; - dacryocystitis; - keratitis; - cornea ulcer; - chlamydial eye infection. Prevention and treatment of bacterial infections after eye injuries and surgical interventions.
Contraindications
- pregnancy; - lactation (breastfeeding); - hypersensitivity to the drug.
Use during pregnancy and lactation
Data on the negative effects of ofloxacin on the fetus are not available, however, the drug is contraindicated for use during pregnancy and lactation (breastfeeding).
Dosage and administration
The drug in the form of eye drops prescribed by 1 drop in the lower conjunctival sac of the affected eye 2-4 times / day. It is not recommended to use the drug for more than 2 weeks. If you need to use more than one drug at the same time, the minimum interval between instillations is 5 minutes. When using the drug in the form of an eye ointment, 1.5 cm ointment strips are laid at the lower eyelid of the affected eye 2-3 times / day; in case of chlamydial infection - 5 times / day. It is not recommended to use the drug for more than 2 weeks. A combination of eye drops and Floxal ointment is possible. If you apply more than one ointment at the same time, you should use the last one.
Side effects
Possible: allergic reactions, transient conjunctival hyperemia, burning sensation, discomfort in the eyes, itching and dryness of the conjunctiva, photophobia, tearing. Rare: dizziness.
Overdose
Data overdose Floxal no.
Interaction with other drugs
Drug interaction drug Floxal not described.
special instructions
It is not recommended to wear contact lenses while using the drug. Wear sunglasses (due to the possible development of photophobia) and avoid prolonged exposure to bright light. Effect on the ability to drive and control machinery car and work with mechanisms.