Furasol powder for solution 100mg N15
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Active ingredients
Furazidin
Composition
1 pack (1 g) Furazidine potassium 100 mg. Excipients: sodium chloride - 900 mg.
Pharmacological effect
Antimicrobial drug, a derivative of nitrofuran. Effective against gram-positive cocci (Staphylococcus spp., Streptococcus spp.), Gram-negative rods (Scherichia coli, Salmonella spp., Shigella spp., Klebsiella spp.). Acinetobacter spp. Resistant, most Proteus spp. Strains, Serratia spp. The mechanism of action is associated with inhibition of nucleic acid synthesis. Depending on the concentration has a bactericidal or bacteriostatic effect. Against most of the bacteria, the bacteriostatic concentration ranges from 10-20 mcg / ml. The bactericidal concentration is about 2 times higher. Under the influence of nitrofurans in microorganisms, the activity of the respiratory chain and the tricarboxylic acid cycle (Krebs cycle) is suppressed, as well as the suppression of other biochemical processes, which leads to the destruction of their membrane or cytoplasmic membrane. Nitrofurans increase complement titer and the ability of leukocytes to phagocytose microorganisms.
Pharmacokinetics
Data on the pharmacokinetics of the drug Furasol not provided.
Indications
With complex treatment: - infectious and inflammatory diseases of the oral cavity, oropharynx - small wounds with the threat of infection (including abrasions, scratches, minor cuts and scratches, cracks, mild burns).
Contraindications
- allergic dermatitis - pregnancy - lactation period (breastfeeding) - children's age up to 4 years - hypersensitivity to furazidine or nitrofuran preparations.
Use during pregnancy and lactation
Use of the drug is contraindicated during pregnancy and lactation.
Dosage and administration
The drug is intended for local and external use. The solution is prepared immediately before use. The contents of the bag are dissolved in 200 ml of hot water. Locally: a warm solution is used to rinse the mouth and oropharynx 2-3 times / day. External: warm solution is used for washing wounds 1-2 times / day. Duration of treatment is 3-5 days.
Side effects
The classification of adverse reactions according to the frequency of development: very often (10%), often (1%, but less than 10%), infrequently (0.1%, but less than 1%), rarely (0.01%, but less than 0.1%), very rarely ( less than 0.01%), the frequency is unknown (it is impossible to determine from the available data). Allergic reactions: frequency is unknown - urticaria, pruritus, rash, allergic dermatitis.If unusual reactions occur, the patient should consult a doctor about the appropriateness of further use of the drug.
Overdose
The drug has low toxicity. Cases of overdose are not described.
Interaction with other drugs
In combination with antibiotics, it shows synergism. In the case of alcohol during drug treatment, the likelihood of allergic skin reactions increases.
special instructions
With the development of adverse reactions, the drug should be canceled and prescribe symptomatic therapy. The solution is prepared immediately before use. Do not store the prepared solution. Influence on the ability to drive vehicles and control mechanisms The use of the drug does not affect the ability to drive vehicles and mechanisms.