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Active ingredients
Betamethasone + Salicylic Acid
Release form
Ointment
Composition
Betamethasone dipropionate 640 mcg, which corresponds to the content of betamethasone 500 mcg, salicylic acid 30 mg. Auxiliary substances: liquid paraffin - 100 mg, vaseline - 869.36 mg.
Pharmacological effect
Ointment Diprosalic is a combined preparation based on two active substances - betamethasone dipropionate and salicylic acid. Betamethasone dipropionate - synthetic fluorinated GCS - has anti-inflammatory, antipruritic and vasoconstrictive effect. When applied locally, salicylic acid has keratolytic and bacterio-stimulating, as well as bacterio-stimulating, bacterio-stimulating, and bacterio-stimulating, anti-inflammatory properties.
Indications
Ointment Diprosalik is indicated to reduce the inflammatory manifestations of dry and hyperkeratic dermatoses sensitive to GCS therapy, including: - psoriasis; - chronic atopic dermatitis; - neurodermatitis (chronic simple lichen); - lichen planus; - eczema (including Coin-like eczema, hand eczema, eczematous dermatitis); - dyshidrosis; - seborrheic dermatitis of the scalp; - ichthyosis and other ichthyosis-like conditions.
Contraindications
- an indication of hypersensitivity reactions to any of the components of the ointment in history.
Precautionary measures
Use in children The drug can be used with caution in children from the age of 2 years.
Use during pregnancy and lactation
Due to the fact that the safety of use of local corticosteroids in pregnant women has not been established, the prescription of this class of drugs during pregnancy is justified only if the expected benefit to the mother exceeds the potential risk to the fetus. Preparations of this class should not be used during pregnancy in large doses or for a long time. Since so far it has not been revealed whether the level of systemic absorption of local corticosteroids is sufficient for the appearance of their detectable concentrations in mother’s milk, Kratom breastfeeding or use of the drug, taking into account the extent necessary for the mother.
Dosage and administration
Ointment Diprosalik should be applied with a thin layer 2 times a day - in the morning and at night, completely covering the affected skin.In some patients, a supportive effect can be achieved with less frequent applications.
Side effects
Adverse events that occurred while using local corticosteroids included burning, itching, irritation, dry skin, folliculitis, hypertrichosis, acne-like rashes, hypopigmentation, perioral dermatitis, allergic contact dermatitis. The following phenomena are more frequent when using occlusive dressings: maceration of the skin, secondary infection, atrophy of the skin, striae and prickly heat. Salicylic acid preparations can cause dermatitis. If adverse reactions that are not described in this manual occur, you should consult a doctor.
Overdose
Excessive and prolonged use of GCS for local use can cause inhibition of the function of the pituitary-adrenal system, leading to secondary adrenal insufficiency and symptoms of hypercorticism, including Cushing's syndrome. Corresponding symptomatic treatment is shown. The acute symptoms of hypercorticism are usually reversible.
special instructions
If during the application of the ointment Diprosalik, irritation or hypersensitization has developed, treatment should be stopped. In case of an infection, appropriate therapy should be prescribed. adrenal system. Systemic absorption of GCS and salicylic acid when applied topically will be higher when using occlusive dressings, as well as in the case of use on extensive erhnostyah tela.Pri long-term drug treatment, it is recommended the abolition postepenno.Maz Diprosalik is not intended for use in ophthalmology. Contact with eyes and mucous membranes should be avoided. Use in pediatrics. The drug can be used with caution in children from 2 years of age. Children are more at risk of suppressing the function of the hypothalamic-pituitary-adrenal system due to the use of local GCS than adults, for a larger ratio they have the surface area of the body and weight and, consequently, increased absorption of the drug. There were reports of a decrease in the function of the hypothalamic-pituitary-adrenal system, Cushing syndrome, growth retardation, not sufficient weight gain and increased intracranial pressure in children who received GCS for local use.Inhibition of the function of the hypothalamic-pituitary-adrenal system in children is determined by low plasma cortisol and a lack of response to the stimulation of adrenocorticotropic hormone. Increased intracranial pressure is manifested by protrusion of the fontanel, headaches, bilateral edema of the optic nerve head.