Buy Baklosan tablets 10 mg 50 pcs

Baklosan pills 10 mg 50 pcs

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Active ingredients


Release form



1 tablet contains: Active substance: baclofen 10 mg.; Excipients: lactose, potato starch, gelatin, talc, magnesium stearate, ethylcellulose.

Pharmacological effect

; Baklosan is a centrally acting muscle relaxant. Baklosan contains the active ingredient baclofen - a derivative of gamma-aminobutyric acid. Baclofen reduces the excitability of the terminal parts of afferent sensory fibers and suppresses intermediate neurons, as a result of which the mono- and polysynaptic transmission of nerve impulses is inhibited. Baclofen helps to reduce the preload of muscle spindles. ; The drug Baklosan has no effect on neuromuscular transmission. ; In patients with neurological diseases that are accompanied by spasticity of skeletal muscles, the drug Baklosan reduces clonic convulsions and painful spasms. Baclofen contributes to increased movement in the joints and facilitates active and passive kinesitherapy (including massage, manual therapy and exercise). ; After oral administration, baclofen is well absorbed in the digestive tract and reaches peak plasma concentrations within 2-3 hours after ingestion. About 30% of the accepted dose of baclofen binds to plasma proteins. ; The active ingredient of the drug Baklosan penetrates through the hemato-placental barrier and is determined in breast milk. ; A minor portion of baclofen is metabolized in the liver. Excreted mainly by the kidneys in the form of an unchanged substance. ;


; Baklosan is used to treat patients with increased muscle tone in multiple sclerosis, cerebrovascular diseases, meningitis, cerebral palsy, as well as diseases of the spinal cord, including motor motor neuron diseases, tumors, syringomyelia and myelitis. ; Corlosan may be prescribed to patients with increased muscle tone, which has developed as a result of traumatic brain injury or spinal cord injury.


psychosis; ;Parkinson's disease; ;epilepsy; convulsions (including anamnesis); peptic ulcer and duodenal ulcer; ; lactase deficiency, lactose intolerance, glucose-galactose malabsorption; ;pregnancy; lactation (breastfeeding); hypersensitivity to baclofen.With caution, the drug is prescribed for cerebrovascular insufficiency, cerebral atherosclerosis, chronic renal failure, in elderly patients, children under 3 years.

Use during pregnancy and lactation

; The drug is contraindicated for use during pregnancy and lactation (breastfeeding). ;

Dosage and administration

; Baklosan is intended for oral administration. It is recommended to take the drug Baklosan during meals, drinking plenty of drinking water or tea. If necessary, the tablet can be divided (pills containing 10 mg of the active substance, have a separation risk). If you skip the next dose, you should not take a double dose of baclofen. The duration of therapy and the dose of the drug Baklosan is determined by the doctor. ; Adults, as a rule, at the beginning of therapy, they receive 5 mg of baclofen three times a day. 3 days after the start of therapy, the dose is increased to 20 mg per day. If necessary, a further increase in dose is carried out with an interval of 3 days, increasing the daily dose by no more than 5 mg of baclofen per one dose increase. It is recommended that patients with hypersensitivity, as well as elderly patients, increase the dose more slowly. ; The final dose is established in such a way that a decrease in muscle tone does not cause the development of excessive myasthenia and does not impair motor functions. ; The average therapeutic dose of the drug Baklosan is 30-75 mg. ; The recommended dose for patients with chronic renal failure is 5 mg of baclofen per day. The highest daily dose of baclofen for adults is 100 mg. ; As a rule, at the beginning of therapy, children are prescribed to take 5 mg of baclofen three times a day. If necessary, the dose is gradually increased (with mandatory monitoring of the patient’s condition, the dose is increased with an interval of 3 days by no more than 5 mg per one dose increase). ; The average therapeutic dose for children from 3 to 6 years is 20-30 mg of baclofen per day. ; The average therapeutic dose for children from 6 to 10 years is 30-60 mg of baclofen per day. ; The average therapeutic dose of baclofen for children over 10 years is 2.5 mg / kg body weight per day, but not more than 75 mg per day.; The withdrawal of the drug Baklosan should be carried out gradually (it is recommended to reduce the dose of baclofen within 1-2 weeks).

Side effects

; Depending on the incidence, the following groups of side effects are distinguished: very rare - less than 0.01%, rare - more than 0.01% and less than 0.1%, infrequent - more than 0.1% and less than 1%, frequent - more than 1% and less than 10%, very frequent - more than 10%. ; On the part of the nervous system: very frequent - drowsiness, sedation; frequent dizziness, weakness, fatigue, confusion, gait disturbance, insomnia, euphoria, depression, asthenia, ataxia, tremor, hallucinations, nightmares, nystagmus, dry mouth; rare - paresthesia, dysarthria. ; On the part of the cardiovascular system: frequent - reduction of cardiac output, arterial hypotension. ; From the digestive tract: very frequent - nausea; frequent - vomiting, constipation, diarrhea, dyspeptic symptoms; rare - abdominal pain, dysgeusia, abnormal liver function. ; On the part of the respiratory system: frequent - respiratory depression. ; From the musculoskeletal system: frequent - myalgia. ; On the part of the senses: frequent - paresis of accommodation, visual disturbances. ; On the part of the skin and subcutaneous tissue: frequent - hyperhidrosis, rash. From the kidneys and urinary system: frequent - polyuria, enuresis, dysuria; rare - urinary retention. ; Reproductive system: rare - erectile dysfunction. ; General disorders: very rare - hypothermia. ; In isolated cases, an increase in spasticity was observed, which was regarded as a paradoxical reaction to the drug.


; Symptoms: hypotonia, depression of the respiratory center, confusion, coma (after regaining consciousness, hypotension can persist for 72 hours). ; Treatment: drink plenty of fluids, diuretic intake, respiratory depression - mechanical ventilation. There is no specific antidote.

Interaction with other drugs

; With simultaneous use of Baklosan enhances the effect of drugs that affect the central nervous system, antihypertensive, anti-gout agents, ethanol. With the simultaneous use of Baklosan with tricyclic antidepressants, a significant decrease in muscle tone is possible. ; While taking Baklosan with levodopa and carbidopa, hallucinations, confusion, agitation can occur.

special instructions

; Side effects often have a transient nature, they should be distinguished from the symptoms of the disease about which the treatment is carried out: with concomitant epilepsy, treatment is carried out without discontinuation of anti-epileptic drugs. ; In patients with liver disease and diabetes, it is necessary to periodically monitor the activity of hepatic transaminases and alkaline phosphatase, as well as blood glucose. ; Impact on the ability to drive vehicles and control mechanisms; Patients taking Baklosan, should refrain from potentially hazardous activities associated with the need for increased attention and quick psychomotor reactions.