Buy Bisoprolol-OBL tablets coated 5mg N30

Bisoprolol-OBL pills coated 5mg N30

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Active ingredients

Bisoprolol

Release form

Pills

Composition

Bisoprolol hemifumarate 5 mg

Pharmacological effect

Beta1-selective (selectively blocking beta-receptors) adrenoblocker. It has hypotensive (reducing blood pressure) and antianginal (anti-ischemic) action. By blocking beta1-adrenoreceptors of the heart, it reduces the heart rate (at rest and under load), cardiac output. It lowers atrioventricular conductivity (conduction of electrical excitation through the heart). In large doses (0.02 g or more), the drug can also block beta2-adrenoreceptors, mainly in the bronchi and vascular smooth muscles.

Indications

Arterial hypertension (persistent rise in blood pressure), prevention of strokes.

Contraindications

Chronic heart failure in the phase of decompensation, atrioventricular block II-III degree; intra atrial blockade to a large extent (impaired electrical excitation of the heart); sick sinus syndrome (heart disease, accompanied by a violation of its rhythm); severe bradycardia (rare pulse), arterial hypotension (systolic / “upper” / blood pressure less than 90 mm Hg); bronchial asthma and other diseases that occur with broncho-obstructive syndrome (narrowing of the lumen of the bronchi with impaired sputum outflow); severe peripheral circulation disorders; simultaneous administration of MAO inhibitors; hypersensitivity to the drug and related drugs.

Precautionary measures

During treatment, psoriasis may worsen. During pheochromocytoma, propranolol can only be used after taking an alpha blocker. After a long course of treatment, propranolol should be discontinued gradually, under the supervision of a physician. during anesthesia, you must stop taking propranolol or find a remedy for anesthesia with minimal negative inotropic effects. The impact on the ability to drive vehicles and control mechanisms of patients whose activities require increased attention, the question of the use of propranolol on an outpatient basis should be addressed only after evaluating the individual response of the patient.

Dosage and administration

The dose is selected individually. The average dose of the drug is 0.005-0.01 g.The drug is taken 1 time per day, usually in the morning on an empty stomach or during breakfast. The pill should be swallowed whole with a liquid. With a small degree of increase in blood pressure, the initial dose of the drug may be 0.0025 g / day. The excess of the average daily dose of the drug is allowed only in exceptional cases. The drug is usually administered for a long time. In patients with impaired renal function and severe liver function, the daily dose of the drug should not exceed 0.01 g.

Side effects

Fatigue, dizziness, feeling of hot flashes to the face, headaches, sleep disorders, orthostatic hypotension (decrease in blood pressure during the transition from horizontal to vertical position), bradycardia (pulse reduction), impaired atrioventricular conduction (conducting the electrical excitation through the heart). In some patients, it is possible to increase heart failure with the development of peripheral edema. In patients with intermittent claudication (a symptom of a violation of the blood supply to the lower extremities) or those suffering from Raynaud's syndrome (narrowing of the lumen of the extremity vessels) - an increase in the main manifestations of the disease. Reduced tolerance to glucose, especially in patients with concomitant diabetes, including latent (characterized by the absence of clinical symptoms of the disease).

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