Diclofenac Akrikhin gel 1% 40g
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Active ingredients
Diclofenac
Release form
Gel
Composition
100 g of the drug contains diclofenac sodium - 1.0 g. Excipients: dimethyl sulfoxide (dimexide), macrogol (polyethylene oxide 1500), macrogol (polyethylene oxide 400), propylene glycol, succinic acid.
Pharmacological effect
Inhibited by cyclo-oxygenase 1 and type 2, it disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation. Diclofenac is used to eliminate pain and reduce puffiness associated with the inflammatory process. With the recommended method of application of the drug is absorbed no more than 6% diclofenac.
Indications
Post-traumatic inflammation of soft tissues and joints, for example due to sprains, overstresses and bruises. Rheumatic diseases of soft tissues (tendovaginitis, bursitis, periarticular tissue damage); Pain and swelling associated with diseases of the muscles and joints (rheumatoid arthritis, osteoarthritis, radiculitis, lumbago, sciatica).
Contraindications
Hypersensitivity to diclofenac or other components of the drug, as well as to salicylates or other nonsteroidal anti-inflammatory drugs, an indication of a history of asthma attacks after the use of NSAIDs and salicylates; pregnancy (III trimester), lactation, child age (up to 6 years), violation of the integrity of the skin. With care: hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe violations of the liver and kidneys, chronic heart failure, asthma, old age, pregnancy I and II trimester.
Precautionary measures
Use for violations of liver functionWith caution, you should use the drug for severe violations of liver function. Use for violations of renal functionWith caution, you should use the drug for severely impaired renal function. elderly patients.
Use during pregnancy and lactation
Use of the drug in the III trimester of pregnancy is contraindicated.The use of the drug in the I and II trimesters is possible only after consulting a doctor. Experience with the use of the drug during lactation is absent.
Dosage and administration
Outwardly. For adults and children over 12 years old, Diclofenac-Acri is applied to the skin 3-4 times a day and lightly rubbed. The required amount of the drug depends on the size of the painful area. A single dose of the drug - 2-4 g (which is comparable in volume, respectively, with the size of a cherry or walnut). Children from 6 to 12 years old use no more than 2 g of the drug up to 2 times a day. Wash your hands after applying the product. The duration of treatment depends on the indications and the effect noted. After 2 weeks of using the drug should consult a doctor.
Side effects
Local reactions: eczema, photosensitivity, contact dermatitis (itching, redness, swelling of the treated skin area, papules, vesicles, peeling). Systemic reactions: generalized skin rash, allergic reactions (urticaria, angioedema, bronchospasm).
Overdose
Extremely low systemic absorption of the active components of the drug for external use makes overdosing almost impossible.
Interaction with other drugs
The drug can enhance the effect of drugs that cause photosensitivity. Clinically significant interactions with other drugs are not described.
special instructions
The drug should be applied only to intact skin, avoiding contact with open wounds. After application, do not apply an occlusive dressing. Do not allow contact with the eyes and mucous membranes. When using the drug in conjunction with other dosage forms of diclofenac, the maximum daily dose should be considered. When applied to large surfaces of the skin for a long time increases the risk of systemic side effects characteristic of NSAIDs. Before using the drug in patients with gastric ulcer and duodenal ulcer, bronchial asthma, rhinitis, polyps of the nasal mucosa, impaired liver function, kidney or hematopoietic system, as well as the simultaneous use of other NSAIDs need to consult with your doctor.Influence on ability to drive motor vehicles and control mechanisms It does not affect.