Ecofuril capsules 100 mg 30 pcs
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Active ingredients
Nifuroxazide
Release form
Capsules
Composition
1 capsule contains: active ingredient: nifuroksazid 200 mg, excipients: sucrose - 71 mg; corn starch - 68 mg; MCC - 9 mg; magnesium stearate - 2 mg shell: gelatin; titanium dioxide; iron dye oxide yellow.
Pharmacological effect
A broad-spectrum antimicrobial agent for the treatment of gastrointestinal infections (intestinal antiseptic), a nitrofuran derivative. In high doses has a bactericidal effect, in smaller - bacteriostatic. Active against gram-positive bacteria: Staphylococcus spp., Streptococcus spp .; Gram-negative bacteria: Salmonella spp., Shigella spp., Proteus spp.
Pharmacokinetics
After oral administration, nifuroxazide is practically not absorbed from the digestive tract and exerts its antibacterial action exclusively in the intestinal lumen. Fully excreted through the digestive tract. The rate of elimination depends both on the dose of the drug and on the motility of the intestinal tract.
Indications
Acute diarrhea of bacterial genesis (in the absence of suspicion of invasion).
Contraindications
Hypersensitivity to nitrofuran derivatives. Do not use in newborns (up to 1 month old) and premature babies.
Use during pregnancy and lactation
There are no data on adverse effects on the fetus during pregnancy. If necessary, with caution, the drug can be prescribed to pregnant women and women who are breastfeeding.
Dosage and administration
Adults - 200 mg 4 times / day. Children aged 1 month to 2.5 years - 100 mg 2-3 times / day; over 2.5 years old - 200 mg 3 times / day. Duration of treatment is no more than 7 days.
Side effects
Possible: allergic reactions.
Overdose
The specific symptoms of overdose are not described. Treatment: Standard emergency measures are recommended.
Interaction with other drugs
Simultaneous use of ethanol may cause symptoms of hypersensitivity.
special instructions
When treating diarrhea, nifuroxazide should be given simultaneously with oral and intravenous rehydration therapy in accordance with the patient's condition and the duration of diarrhea. During therapy with nifuroxazide, alcohol is not allowed.Impact on the ability to drive motor vehicles and control mechanisms The drug does not adversely affect the ability to drive vehicles and / or other mechanisms.