Solcoderm solution outer ampoules 0,2ml N1
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Active ingredients
Nitric acid + Acetic acid + Oxalic acid dihydrate + Lactic acid + Copper nitrate trihydrate
Release form
Solution
Composition
Indomethacin. Excipients: microcrystalline cellulose - 48.6 mg, potato starch - 16.2 mg, methacrylic acid copolymer - 5.4 mg, talc - 1.8 mg, magnesium stearate - 3 mg.
Pharmacological effect
Combined preparation for external use. After application to the affected area, it penetrates the treated tissue and, after 1–2 minutes, causes a change in its color, which reflects the lifetime fixation of the tissue of the treated area. Later, mummification of the pathological tissue occurs, the eschar darkens and disappears on its own in a few days. Healing happens quickly. Complications (in the form of secondary infection or scarring) are rare. The development of systemic effects is unlikely.
Pharmacokinetics
The complex effect of components of Solcoderm - nitric acid, copper nitrate and organic acids (acetic, lactic, oxalic acids) on the affected area of the skin provides for the rapid devitalization and fixation of the pathologically changed section of the treated tissue. During therapy with Solcoderm, no significant absorption of the active substances through the skin is observed; taking into account the minimum amount of therapeutic dose, you can not fear the systemic effects of the drug on the body
Indications
Topical treatment of superficial benign lesions of the skin, including simple and plantar warts; genital warts; seborrheic keratosis; nevus (with confirmed good quality process).
Contraindications
Malignant skin tumors prone to metastasis (melanoma); freckles; keloid scars
Precautionary measures
Do not use on inflamed areas of the skin. In cases of pain, treatment should be promptly interrupted. Using too large doses can cause acid burns and damage to deep tissue layers. Special precautions should be observed when applying Solkoderma solution to the face, especially on skin areas located near the eyes.If an accidental contact of the Solcoderm solution into the eye has occurred, it is necessary to immediately rinse the eye with a large amount of water or a weak alkaline solution, for example, 1% sodium bicarbonate solution. Drops of Solcoderm solution falling on furniture or clothing should be washed off with water, since Solcoderm is capable of destroying materials. After biopsy of the affected skin area, it is recommended to wait 8–10 days before starting treatment. Special care is required when treating benign skin tumors previously treated with other drugs and methods. Before discarding the ampoule, the remnants of the solution should be washed off in running water. Empty vial can be thrown into the trash.
Use during pregnancy and lactation
Treatment with Solcoderm during pregnancy is carried out only in cases where the benefit to the mother exceeds the risk to the fetus.
Dosage and administration
Treatment must be carried out by a doctor or specially trained medical personnel. Due to the instability of the p-ra in the open vial for each application, you must use a new vial. An open ampoule can be fixed in a special recess in the package. Before the procedure, the affected skin is treated with alcohol or ether. Solcoderm applied directly to the affected skin. For applying the drug in each package there is an applicator with sharp and blunt ends and a glass tube. The sharp end of the applicator is intended for the treatment of small area lesions, the blunt end is intended for the treatment of extensive and / or keratinous lesions. Using a glass tube, surfaces of up to 4–5 cm2 can be processed. For adults and children, Solcoderm is gently applied to the affected area with an applicator or glass tube and then penetrated with a plastic applicator until the solution is completely absorbed. Over the next 3-5 minutes it is necessary to pay attention to the appearance of grayish or yellowish color of the treated skin. If necessary, the procedure should be repeated until the indicated color appears. Damage zones near mucous membranes and eyes should be treated with extreme caution. When treating keratinized warts, part of the stratum corneum may be previously removed.Neoplasms with a diameter of> 10 mm are treated with Solcoderm only if only the upper layer of the skin is affected. With multiple lesions, drug treatment should be carried out in several stages with an interval of about 4 weeks. In one session, 4–5 skin neoplasms with a total area of no more than 4–5 cm2 can be processed. For several days after treatment, the affected area is covered with a mummified dark brown scab. If mummification is not satisfactory, the treatment can be repeated after a few days.
Side effects
Sensation of slight short-term local burning. In case of a pronounced reaction on the adjacent skin areas, a cream containing GCS or an ointment containing anesthetics can be applied. In the case of treatment of deep skin lesions, after depot treatment, depigmented spots or scars may remain.
Overdose
An ulcer resulting from an overdose is subject to standard topical treatment.
Interaction with other drugs
Not described
special instructions
For the normal course of the mummification process, the tumor on which Solcoderm was applied should be treated with 70% alcohol, especially after taking a bath / shower. The scab should not be removed, it should fall off on its own. Until complete healing, direct exposure to sunlight and UV radiation should be avoided. If the drug gets on the mucous membranes or healthy skin, it is necessary to quickly wash it off with a large amount of water or 1% solution of sodium bicarbonate. When surgical removal of the affected area of the skin preceding the use of Solcoderm, treatment should begin no earlier than after 8–10 days. Patients with a tendency to the formation of coarse scars should not be prescribed Solcoderm. Before discarding used ampoules, the remnants of the p-ra should be washed with running water.