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Active ingredients
Interferon gamma
Release form
Pills
Composition
Active ingredient: antibodies to human gamma interferon affinity-purified - 0, 003 g Active substance concentration (mg): antibodies to human gamma interferon affine-purified - 0, 003 g
Pharmacological effect
The drug that activates antiviral immunity. With prophylactic and therapeutic use of the drug has an immunomodulatory and antiviral effect. Efficacy against influenza viruses (including avian influenza), parainfluenza, herpes simplex viruses of types 1 and 2 (labial herpes, genital herpes), other herpes viruses (chickenpox, infectious mononucleosis), enteroviruses, tick-borne virus has been experimentally and clinically established. encephalitis, rotavirus, coronavirus, calicivirus, adenovirus, respiratory syncytial (PC virus). The drug reduces the concentration of the virus in the affected tissues, affects the system of endogenous interferons and associated cytokines, induces the formation of endogenous early interferon (IFN α / β) and gamma interferon (IFNγ). Stimulates the humoral and cellular immune response. It increases the production of antibodies (including secretory IgA), activates the functions of T-effectors, T-helpers (Tx), normalizes their ratio. Increases the functional reserve of Tx and other cells involved in the immune response. It is an inducer of the mixed Tx1 and Tx2-type immune response: it increases the production of cytokines Tx1 (IFNγ, IL-2) and Tx2 (IL-4, 10), normalizes (modulates) the balance of Tx1 / Tx2 activities. Increases the functional activity of phagocytes and natural killer cells (EC cells). It has antimutagenic properties.
Pharmacokinetics
Data on the pharmacokinetics of the drug is not provided.
Indications
Prevention and treatment of acute respiratory viral infections (including influenza). Combined therapy of infections caused by herpes viruses (infectious mononucleosis, chickenpox, labial herpes, genital herpes). Combined therapy and prevention of recurrence of chronic herpes virus infection, including labial and genital herpes. Combined therapy and prevention of other acute and chronic viral infections caused by tick-borne encephalitis virus, enterovirus, rotavirus, coronavirus, calicivirus. Application as part of complex therapy of bacterial infections. Complex therapy of secondary immunodeficiency states of various etiologies, including prevention and treatment of complications of viral and bacterial infections.
Contraindications
Increased individual sensitivity to the components of the drug. Children and persons under the age of 18 are shown to use the drug Anaferon for children.
Precautionary measures
Do not exceed recommended doses.
Use during pregnancy and lactation
The safety of using Anaferon during pregnancy and lactation has not been studied. If necessary, taking the drug should consider the ratio of risk / benefit.
Dosage and administration
Inside At one time - 1 tablet (keep in the mouth until completely dissolved - not during the meal). SARS, influenza, intestinal infections, herpes virus infections, neuroinfections. Treatment should begin as soon as possible - when the first signs of an acute viral infection appear as follows: during the first 2 hours, the drug is taken every 30 minutes, then during the first day, three more doses are taken at regular intervals. From the second day on and on take 1 tablet 3 times a day until complete recovery. In the absence of improvement, on the third day of treatment with a drug of acute respiratory viral infections and influenza, one should consult a doctor. In the epidemic season, for preventive purposes, the drug is taken daily 1 time per day for 1-3 months. Genital herpes. For acute manifestations of genital herpes, the drug is taken at regular intervals as follows: 1-3 days - 1 tablet 8 times a day, then 1 tablet 4 times a day for at least 3 weeks. For the prevention of recurrence of chronic herpes virus infection - 1 tablet per day. The recommended duration of the prophylactic course is determined individually and can reach 6 months. When using the drug for the treatment and prevention of immunodeficiency states, in the complex therapy of bacterial infections, take 1 tablet per day. If necessary, the drug can be combined with other antiviral and symptomatic agents.
Side effects
When using the drug for the indicated indications and in the indicated dosages, no side effects were revealed. Possible manifestations of increased individual sensitivity to the components of the drug.
Overdose
Cases of overdose so far not registered.In case of accidental overdose, dyspeptic symptoms are possible due to the fillers in the preparation.
Interaction with other drugs
Cases of incompatibility with other drugs have not yet been identified. If necessary, the drug can be combined with other antiviral, antibacterial and symptomatic agents.
special instructions
The preparation contains lactose, therefore it is not recommended to prescribe it to patients with congenital galactosemia, glucose malabsorption syndrome or in congenital lactase deficiency.