Celestoderm B with garamycin ointment for external use 30 g
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Description
Uniform ointment from almost white to light yellow color of a soft consistence, not containing foreign inclusions.
Active ingredients
Betamethasone + Gentamicin
Release form
Ointment
Composition
1 g ointment contains: active ingredients: betamethasone 17-valerate - 1.22 mg (equivalent to 1.0 mg betamethasone) and gentamicin sulfate - equivalent 1.0 mg (1000 IU) gentamicin; excipients: liquid paraffin - 100.0 mg, white soft paraffin - 898.78 mg.
Pharmacological effect
Ointment Celestoderm-B with Garamicin contains glucocorticosteroid (GCS) betamethasone valerate, which has anti-inflammatory, antipruritic and vasoconstrictor effects, and the antibiotic gentamicin, which has antibacterial activity of a wide spectrum of action. Gentamicin-susceptible bacteria include susceptible strains of Staphylococcus aureus (coagulase-positive, coagulase-negative, and some penicillin-producing strains), as well as Gram-negative bacteria Pseudomonas aeruginosa, Aerobacter aerogenes, Iaurus-i-chi-chi-chi-irius, and I-irai, irai-ius, and I-ius, and I-ius, and I-ius, and I-ius,.
Indications
Local treatment of skin diseases susceptible to corticosteroids, in the presence of a secondary infection caused by susceptible gentamicin microorganisms, or if such an infection is suspected: eczema (atopic, pediatric, monomatous), contact dermatitis, seborrheic dermatitis, neurodermatitis, solar dermatitis, exfoliative dermatitis, radiation dermatitis, diaper rash, psoriasis, anogenital and senile itching. The ointment is used for skin lesions on the background of eczema and psoriasis.
Use during pregnancy and lactation
Due to the fact that the safety of using local corticosteroids in pregnant women has not been established, the prescription of drugs of this class during pregnancy is justified only if the benefit to the mother clearly exceeds the possible harm to the fetus. Drugs in this group should not be used in pregnant women in large doses or for a long time. Since it has not yet been established whether GCS, when applied topically and systemically absorbed, can penetrate into breast milk, breastfeeding or use of the drug should be discontinued, considering how much its use is necessary for the mother.
Dosage and administration
Outwardly. Ointment Celestoderm-B should be applied with a thin layer to the affected areas 1-3 times a day, depending on the severity of the condition. In most cases, to achieve the effect is sufficient application 1-2 times a day.
Side effects
When using GCS of local action, the following undesirable phenomena were observed: burning, irritation and dry skin, folliculitis, hypertrichosis, acne-like rashes, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, secondary infection, skin atrophy, stria and strepitis.
Overdose
Symptoms Excessive or prolonged use of local corticosteroids can cause inhibition of the function of the pituitary-adrenal system, which can cause the development of secondary insufficiency of the adrenal cortex and the appearance of symptoms of hypercorticism, including Cushing syndrome. Treatment. Corresponding symptomatic treatment is indicated. The acute symptoms of hypercorticism are usually reversible. If necessary, correction of electrolyte imbalance is shown. In the case of chronic toxic effects, the gradual abolition of corticosteroids is recommended.
Interaction with other drugs
No interaction of the drug Celestoderm-B with other drugs is not registered.
special instructions
In the absence of the effect of treatment within 2 weeks, it is recommended to contact your doctor for possible clarification of the diagnosis. If the use of the drug marked irritation or hypersensitivity reaction, treatment should be discontinued and the patient should be treated with adequate therapy. For secondary fungal or bacterial infection, appropriate medications should be prescribed. In the absence of a quick positive effect, the use of corticosteroids should be discontinued until all signs of infection have been eliminated. Any side effects of systemic corticosteroids, including suppression of the function of the adrenal cortex, can also be observed when using local corticosteroids, especially in children. Systemic absorption of local corticosteroids is enhanced with their long-term use, with the treatment of large areas of the body or with the use of covering dressings, as well as in children. Celestoderm-B is indicated for external use only and is not intended for use in ophthalmology. Application in pediatric practice: Celestoderm ointment-Vmozhet be used to treat children from the age of 6 months. Children may be susceptible to the use of local GCS,causing depression of the hypothalamic-pituitary-adrenal system (GGN) than older patients, due to the increased absorption of the drug, associated with a higher ratio of unaligned surface area and body weight. , Cushing's syndrome, linear growth retardation, lag in weight gain, increased intracranial pressure. Symptoms of depression of the function of the kidney glands in children include a decrease in plasma cortisol levels and a lack of response to stimulation of ACTH. The increase in intracranial pressure is manifested by the swelling of the fontanel, headache, bilateral edema of the optic nerve head. Effect on ability to drive and work with mechanisms: No effect of Celestoderm-B on the ability to drive and work with mechanisms was detected.
Storage conditions
In the reach of children. Store at a temperature not higher than 25 ° С.