Diclovit rectal suppositories 10 pcs
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Active ingredients
Diclofenac
Release form
Suppositories
Composition
1 supp. Diclofenac Sodium 50 mg.
Pharmacological effect
NSAIDs. It has a pronounced anti-inflammatory, analgesic, antipyretic and antiaggregant effect, the mechanism of which is due to the inhibition of the activity of COX-1 and COX-2, which leads to disruption of arachidonic acid metabolism and suppression of prostaglandin synthesis in the inflammatory focus. In rheumatic diseases, the anti-inflammatory and analgesic effect of diclofenac significantly reduces the severity of pain, morning stiffness, swelling of the joints, which improves the functional state of the joints. It helps to increase the range of motion in the affected joints. With traumatic and postoperative pain, the drug reduces pain, as well as the severity of inflammatory reactions. When primary algomenorrhea weakens pain and reduces bleeding.
Indications
- inflammatory and degenerative diseases of the joints (including rheumatoid arthritis, ankylosing spondylitis, juvenile arthritis, psoriatic arthritis, acute and chronic gouty arthritis). - rheumatic lesions of soft tissues. - post-traumatic pain syndrome (including traumatic bruises, sprains, muscles and tendons). - muscle and joint pain caused by heavy physical exertion. - lumbago. - sciatica. - neuralgia. - postoperative pain. - primary algomenorrhea, adnexitis. - migraine attacks. - renal and biliary colic. - infectious and inflammatory diseases of upper respiratory tract with severe pain syndrome (including pharyngitis, tonsillitis, otitis media). - fever.
Contraindications
- erosive and ulcerative lesions of the gastrointestinal tract in the acute phase - bleeding from the gastrointestinal tract, rectal bleeding - impaired blood formation of unknown origin - hemorrhoids, proctitis - "aspirin triad" - pregnancy - children's age up to 6 years - hypersensitivity to diclofenac sodium, acetylsalicylic acid and other NSA . With caution prescribed for induced acute hepatic porphyria, impaired renal function and liver, heart failure, during lactation (breastfeeding).
Use during pregnancy and lactation
Diclovit is contraindicated for use in pregnancy.
Dosage and administration
Adults appoint 1 soup. (50 mg) 2 times / day. The maximum daily dose is 150 mg (3 soup.). Migraine attacks: 100 mg (2 soup.) At the first sign of an attack. If necessary, re-appoint 100 mg (2 soup.). If it is necessary to continue treatment in the following days, the daily dose should not exceed 150 mg (3 soup.) Per day. Suppositories are introduced into the rectum after spontaneous cleansing of the intestine or after a cleansing enema. After administration, the patient should be in a lying position for 20-30 minutes The duration of the course of therapy is determined by the doctor individually, depending on the severity of the disease.
Side effects
On the part of the digestive system: gastralgia, nausea, vomiting, diarrhea, stomach pain, dyspepsia, constipation, flatulence, anorexia, increased activity of liver transaminases, gastrointestinal bleeding, hepatitis (including jaundice), fulminant hepatitis, pancreatitis, non-specific colitis with bleeding, exacerbation of ulcerative colitis or Crohn's disease. On the part of the central nervous system and peripheral nervous system: headache, dizziness, fatigue, impaired perception, paresthesia, memory loss, loss of orientation, decreased visual acuity, diplopia, hearing loss, tinnitus, insomnia, irritability, convulsions, depression, anxiety, nightmares, tremor, psychotic reactions, taste disturbance. Urinary system: acute renal failure, hematuria, proteinuria, interstitial nephritis, nephrotic syndrome, papillary necrosis. From the hematopoietic system: thrombocytopenia, leukopenia, agranulocytosis, hemolytic anemia, aplastic anemia. Dermatological reactions: rash, bullous eruptions, eczema, erythema multiforme, exfoliative dermatitis, alopecia, purpura. Allergic reactions: bronchospasm, urticaria, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), allergic purpura, photosensitization, systemic anaphylactic reactions (including shock). Others: edema, impotence, chest pain, palpitations, increased blood pressure. Local reactions: irritation of the mucous membrane of the colon, mucous discharge with blood, pain during defecation.The resulting side effects depend on the individual sensitivity, the magnitude of the applied dose and the duration of treatment.
special instructions
On the part of the digestive system: gastralgia, nausea, vomiting, diarrhea, stomach pain, dyspepsia, constipation, flatulence, anorexia, increased activity of liver transaminases, gastrointestinal bleeding, hepatitis (including jaundice), fulminant hepatitis, pancreatitis, non-specific colitis with bleeding, exacerbation of ulcerative colitis or Crohn's disease. On the part of the central nervous system and peripheral nervous system: headache, dizziness, fatigue, impaired perception, paresthesia, memory loss, loss of orientation, decreased visual acuity, diplopia, hearing loss, tinnitus, insomnia, irritability, convulsions, depression, anxiety, nightmares, tremor, psychotic reactions, taste disturbance. Urinary system: acute renal failure, hematuria, proteinuria, interstitial nephritis, nephrotic syndrome, papillary necrosis. From the hematopoietic system: thrombocytopenia, leukopenia, agranulocytosis, hemolytic anemia, aplastic anemia. Dermatological reactions: rash, bullous eruptions, eczema, erythema multiforme, exfoliative dermatitis, alopecia, purpura. Allergic reactions: bronchospasm, urticaria, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), allergic purpura, photosensitization, systemic anaphylactic reactions (including shock). Others: edema, impotence, chest pain, palpitations, increased blood pressure. Local reactions: irritation of the mucous membrane of the colon, mucous discharge with blood, pain during defecation. The resulting side effects depend on the individual sensitivity, the magnitude of the applied dose and the duration of treatment.