Opatanol eye drops 0.1% 5ml
Condition: New product
998 Items
Rating:
Be the first to write a review!
More info
Active ingredients
Olopatadin
Release form
Drops
Composition
In 1 ml. solution: Olopatadin hydrochloride 1.11 mg, which corresponds to the content of olopatadin 1 mg. Auxiliary substances: benzalkonium chloride, sodium chloride, disodium phosphate dodecahydrate, hydrochloric acid and / or sodium hydroxide solution (to maintain the pH level), purified water.
Pharmacological effect
A selective blocker of histamine H1 receptors also inhibits the release of inflammatory mediators from mast cells. It has a pronounced antiallergic effect. It does not affect α-adrenergic receptors, dopamine receptors, M1- and m2-cholinergic receptors, as well as serotonin receptors.
Pharmacokinetics
Absorption: When applied topically, systemic absorption is low. Cmax of olopatadin in plasma is reached within 2 hours after topical administration and ranges from 0.5 ng / ml to less than 1.3 ng / ml. Output: T1 / 2 in plasma is 3 hours. It is eliminated mainly by the kidneys, 60-70% is excreted in unchanged the form.
Indications
Allergic conjunctivitis.
Contraindications
Hypersensitivity to the drug.
Use during pregnancy and lactation
Sufficient experience in the use of the drug during pregnancy and lactation (breastfeeding) no. Use in pregnant women and nursing mothers is possible when the expected therapeutic effect outweighs the potential risk of side effects in the fetus or infant.
Dosage and administration
The drug is instilled 1 drop into the conjunctival sac 2 times / day. Before use, shake the bottle.
Side effects
Local reactions: less than 5% - blurred vision, burning and pain in the eyes, tearing, foreign body sensation in the eye, conjunctival hyperemia, keratitis, iritis, eyelid swelling. Systemic reactions: 0.1-1% - weakness, headache, dizziness, nausea , pharyngitis, rhinitis, sinusitis, taste change.
Overdose
When applied topically, overdose is unlikely. If an excessive amount of the drug gets into the eyes, it is recommended to wash the eyes with warm water.
Interaction with other drugs
Compatible with other ophthalmic preparations for topical use.If necessary, the simultaneous use of the interval between instillations should be at least 5 minutes.
special instructions
Opatanol contains benzalkonium chloride preservative, which can be absorbed by contact lenses. Before instillation of the drug, the lenses should be removed and installed back no earlier than 20 minutes after instillation. Do not touch the pipette tip to any surface to avoid contamination of the solution. Use in pediatrics: Sufficient experience with the drug in children under 3 years of age there is none. Opatanol can be prescribed to children aged 3 years and older in the same doses as adults. Impact on ability to drive vehicles and control mechanisms: If the patient's visual clarity is temporarily reduced after using the drug, it is not recommended to drive the car and do it other activities requiring high concentration of attention and speed of psychomotor reactions.