• Cerebrolysin

    Cerebrolysin

    Cerebrolysin is a complex peptide nootropic drug that is derived from porcine brain. It is used as a cognitive-enhancing agent and as a treatment to various neurologic diseases, such as stroke, traumatic brain injuries, and organic mood disorder. Cerebrolysin is usually well-tolerated and has the history of medical use since the 1950s

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  • picamilon

    Picamilon

    Picamilon is a nootropic drug developed in the 1960s in the Soviet Union. Picamilon is a synthetic combination of GABA and Vitamin B3. The drug has anxiolytic action and improves cerebral blood flow. It is used to treat anxiety, chronic fatigue, and improve cognitive functions.

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  • actovegin

    Actovegin

    Is a calf blood hemodialysate, which contains over 200 endogenous compounds such as peptides, amino acids, and micronutrients. Actovegin is used since the 1960s to treat cerebrovascular disorders and promote healing of injuries. Several studies also suggested that Actovegin can improve symptoms in type 2 diabetes patients and alleviate diabetic neuropathy.

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  • Semax

    Semax

    Semax is a peptide nootropic drug. It was developed in the Soviet Union as a long-acting analog of an adrenocorticotropic hormone, which supposedly involved in memory and learning processes. Semax is used to treat stroke, traumatic brain injuries, and also can be used by healthy individuals for cognitive-enhancing purposes.

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  • afobazole

    Afobazole

    Afobazole is a non-benzodiazepine anxiolytic drug developed in Russia. The drug is non-sedating and not habit-forming, unlike most anxiety drugs, and is shown to possess nootropic activity. Afobazole is used to treat various conditions such as anxiety disorders, irritable bowel syndrome, premenstrual syndrome, and alcohol withdrawal syndrome.

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  • adaptol

    Adaptol

    Adaptol is an anti-anxiety drug that is used in Russia since 1978 to treat anxiety and reduce smoking cravings. The active ingredient of Adaptol is Mebicar. The drug is not habit-forming and does not impair cognitive functions, unlike benzodiazepine tranquilizers. Recent studies also suggest that Adaptol can relieve ADHD symptoms in children.

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  • memantine

    Memantine

    Memantine is an Alzheimer's drug developed in the 1960s. Memantine works by blocking NMDA receptors and is used medically to moderate-to-severe dementia of the Alzheimer's type. The drug is also used recreationally to relieve anxiety, depression, decrease tolerance to the other drugs and for cognitive-enhancing purposes.

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  • selank

    Selank

    Selank is a peptide anxiolytic drug that is used in Russia since 2009 for anxiety disorders. Selank has a good side effects profile and is usually well tolerated. The drug is not addictive and does not impair cognition and motor skills.

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  • noopept

    Noopept

    Noopept is one of the most popular nootropic drugs in the world. It is used recreationally for memory and cognition improvement and is often found in proprietary blend nootropic supplements. Noopept is also used medically in Russia to treat traumatic brain injuries, post-concussion syndrome, and cerebrovascular diseases.

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  • phenibut

    Phenibut

    Phenibut is an anti-anxiety drug that was developed in the Soviet Union in the 1960s as a non-sedating tranquilizer for astronauts. It is a synthetic derivative of gamma-aminobutyric acid. Phenibut is used medically to treat anxiety disorders, and also widely used worldwide as an anti-anxiety supplement. The drug is also shown to possess nootropic effect.

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  • grandaxin

    Grandaxin

    Grandaxin (Tofisopam) is a non-sedating tranquilizer that is used in Russia, Japan, and some European countries to treat anxiety disorders. It is a benzodiazepine anxiolytic, however, tofisopam is not sedative or habit-forming because of its structural difference. Grandaxin does not bind to benzodiazepine receptors and has a unique mechanism of action.

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  • stresam

    Stresam

    Stresam (Etifoxine) is a non-benzodiazepine anxiolytic that is used in more than 40 countries around the world (primarily Russia and South Africa). According to clinical trials, the efficacy of Stresam in the treatment of anxiety is comparable to that of benzodiazepines. The drug also does not impair cognition and is not habit-forming, although it may cause allergic reactions.

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