Buy Exoderil solution 1% 20ml

Exoderil solution 1% 20ml

Condition: New product

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$33.15

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Active ingredients

Naftifine

Release form

Solution

Composition

1 ml of solution contains 10 mg naftifine hydrochloride. Excipients: propylene glycol - 50 mg; ethanol - 400 mg; purified water - 475 mg

Pharmacological effect

Naftifine is an antifungal agent for external use, belonging to the class of allylamines. The mechanism of action is associated with inhibition of squalene-2,3-epoxidase, which leads to a decrease in the formation of ergosterol, which is part of the cell wall of the fungus. It is active against dermatophytes, such as trichophyton, epidermofiton and microsporum, molds (Aspergillus spp.), Yeast fungi (Candida spp., Pityrosporum) and other fungi (for example, Sporothrix schenckii). With respect to dermatophytes and Aspergillus naftifin, there are some fungi, asphgillus spp. In relation to yeast fungi, the drug exhibits fungicidal or fungistatic activity depending on the strain of the microorganism. It has antibacterial activity against gram-positive and gram-negative microorganisms that can cause secondary bacterial infections. It has an anti-inflammatory effect, which contributes to the rapid disappearance of the symptoms of inflammation, especially itching

Pharmacokinetics

Naftifine quickly penetrates the skin, creating stable antifungal concentrations in its various layers, which makes it possible to use it once a day

Indications

Fungal infections of the skin and skin folds (tinea corporis, tinea inquinalis); interdigital mycoses (tinea manum, tinea pedum); fungal infections of the nails (onychomycosis); cutaneous candidiasis; pityriasis versicolor; dermatomycosis (with or without itching). Effective in treating mycoses that affect areas of the skin with hyperkeratosis, as well as in hair growth zones

Contraindications

Hypersensitivity to naftifine or propylene glycol. The preparation should not be applied on the wound surface. With care: children's age (experience of clinical use is limited).

Precautionary measures

Exoderil is not intended for use in ophthalmology. Avoid contact with eyes.

Use during pregnancy and lactation

Safety and efficacy not established.

Dosage and administration

Externally, in case of skin lesions, Exoderil is applied 1 time per day to the affected skin surface and adjacent areas (approximately 1 cm of a healthy skin area at the edges of the lesion area) after thoroughly cleaning and drying them.The duration of treatment for ringworms is 2–4 weeks (up to 8 weeks if necessary), and candidiasis 4 weeks. When the nails are damaged, Exoderil is applied 2 times a day on the affected nail. Before the first use of the drug, remove the affected part of the nail as much as possible with scissors or a nail file. The duration of treatment for onychomycosis is up to 6 months. To prevent relapse, treatment should be continued for at least 2 weeks after the disappearance of clinical symptoms

Side effects

In some cases, there may be local reactions: dry skin, hyperemia and burning. Side effects are reversible and do not require discontinuation of treatment.

Overdose

No cases of overdose have been reported.

Interaction with other drugs

No interactions with other drugs.

special instructions

Influence on ability to drive vehicles and other mechanisms. Exoderil does not adversely affect the ability to drive vehicles and perform other activities that require concentration of attention and speed of psychomotor reactions.

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