Buy Haloperidol-Ozone tablets 1,5mg N50
  1. Home
  2. All products
  3. Haloperidol-Ozone pills 1,5mg N50

Haloperidol-Ozone pills 1,5mg N50

Condition: New product

1000 Items

14,94 $

More info

Description

Ingredients Haloperidol 1.5 mg Pharmacological action Antipsychotic agent (neuroleptic), butyrophenone derivative. It has a pronounced antipsychotic effect due to blockade of depolarization or a decrease in the degree of excitation of dopamine neurons (reduced release) and blockade of postsynaptic dopamine D2 receptors in mesolimbic and mesocortical structures of the brain. It has a moderate sedative effect due to the blockade of.-Adrenergic receptors of the reticular formation of the brain stem. pronounced antiemetic effect due to blockade of dopamine D2 receptors in the trigger zone of the emetic center. hypothermic action and galactorrhea due to blockade of the hypothalamic dopamine receptors. Long-term use is accompanied by a change in the endocrine status, in the anterior lobe of the pituitary gland, prolactin production increases and gonadotropic hormone production decreases. The blockade of dopamine receptors in the dopamine pathways of the black-striped substance contributes to the development of extrapyramidal motor reactions. blockade of dopamine receptors in the tuberoinfundibular system causes a decrease in GH release. Virtually no anticholinergic action. Eliminates persistent changes in personality, delusions, hallucinations, mania, increases interest in the environment. Effective in patients resistant to other neuroleptics. It has some activating effect. In hyperactive children eliminates excessive motor activity, behavioral disorders (impulsivity, difficulty concentrating, aggressiveness). Unlike haloperidol, haloperidol decanoate is characterized by prolonged action.

Dosage and administration

When ingested for adults, the initial dose is 0.5-5 mg 2-3 times / day, for elderly patients - 0.5-2 mg 2-3 times / day. Further, depending on the patient's response to treatment, the dose is gradually increased in most cases to 5-10 mg / day. High doses (more than 40 mg / day) are used in rare cases, for a short time and in the absence of concomitant diseases. For children - 25-75 mg / kg / day in 2-3 doses. With the / m injection for adults, the initial single dose is 1-10 mg, the interval between repeated injections is 1-8 hours. when using the depot form, the dose is 50-300 mg 1 time in 4 weeks. For iv administration, a single dose of 0.5–50 mg, the frequency of administration and the dose for repeated administration depend on the indications and the clinical situation.Maximum doses: for oral administration for adults - 100 mg / day. V / m - 100 mg / day, with the use of the depot form - 300 mg / month. Precautions During the period of treatment may worsen psoriasis. With pheochromocytoma, propranolol can be used only after taking an alpha blocker. After a long course of treatment, propranolol should be discontinued gradually, under the supervision of a physician. Against the background of treatment with propranolol, IV administration of verapamil, diltiazem should be avoided. A few days before anesthesia, you must stop taking propranolol or pick up a remedy for anesthesia with minimal negative inotropic effects. Influence on the ability to drive vehicles and control mechanisms In patients whose activities require increased attention, the question of the use of propranolol on an outpatient basis should be addressed only after evaluating the individual response of the patient. Side Effects From the side of the central nervous system: headache, insomnia, anxiety, anxiety and fear, euphoria, agitation, drowsiness (especially at the beginning of treatment), akathisia, depression or euphoria, lethargy, epilepsy attack, the development of a paradoxical reaction (exacerbation of psychosis, hallucinations ). with long-term treatment, extrapyramidal disorders (including tardive dyskinesia, late dystonia, and anesthesia of the nervous system). Since the cardiovascular system: when used in high doses - arterial hypotension, tachycardia, arrhythmia, ECG changes (increased QT interval, signs of ventricular flutter and fibrillation). On the part of the digestive system: when used in high doses - loss of appetite, dry mouth, hypo-salivation, nausea, vomiting, constipation or diarrhea, abnormal liver function, including the development of jaundice. On the part of the blood system: rarely - light and temporary leukopenia, leukocytosis, agranulocytosis, slight erythropenia and a tendency to monocytosis. On the part of the endocrine system: gynecomastia, pain in the mammary glands, hyperprolactinemia, menstrual disorders, reduced potency, increased libido, priapism. Metabolism: hyper- and hypoglycemia, hyponatremia. increased sweating, peripheral edema, weight gain. On the part of the organ of vision: visual impairment, cataract, retinopathy, accommodation disturbances.Allergic reactions: rarely - skin rash, bronchospasm, laryngism, hyperpyrexia. Dermatological reactions: maculo-papular and acne-like skin changes. rarely - photosensitivity, alopecia. Effects due to cholinergic effects: dry mouth, hypo-salivation, urinary retention, constipation. Specific guidance Not recommended parenteral use in children. It is used with caution in cardiovascular diseases with symptoms of decompensation, myocardial conduction disorders, an increase in the QT interval, or the risk of an increase in the QT interval (including hypokalemia, simultaneous use with drugs that may increase the QT interval). with epilepsy. angle-closure glaucoma. hepatic and / or renal failure. with thyrotoxicosis. pulmonary cardiac and respiratory failure (including in COPD and acute infectious diseases). with prostatic hyperplasia with urinary retention. in chronic alcoholism. simultaneously with anticoagulants. In the case of late dyskinesia, it is necessary to gradually reduce the dose of haloperidol and prescribe another drug. There are reports of the possibility of the appearance of symptoms of non-sugar diabetes, exacerbation of glaucoma, tendencies (with long-term treatment) to the development of lympho-mono-cytosis during the treatment with haloperidol. Elderly patients usually require a smaller initial dose and a more gradual selection of the dose. This cohort of patients is characterized by a high probability of developing extrapyramidal disorders. To identify early signs of tardive dyskinesia, careful monitoring of the patient is recommended. Against the background of neuroleptic treatment, the development of ZNS is possible at any time, but most often it occurs soon after the start of therapy or after transferring a patient from one neuroleptic to another, during a combination treatment with another psychotropic drug or after increasing the dose. During the period of treatment to prevent the use of alcohol. Impact on the ability to drive vehicles and control mechanisms During the period of application of haloperidol should refrain from engaging in potentially hazardous activities that require increased attention and high-speed psychomotor reactions.Use during pregnancy and breastfeeding Haloperidol is contraindicated in pregnancy and lactation. In experimental studies, in some cases, a teratogenic and fetotoxic effect was found. Haloperidol is excreted in breast milk. It has been shown that the concentrations of haloperidol in breast milk are sufficient to cause sedation and impairment of motor functions in an infant. Type: Medicine Quantity in the package, pcs: 50 Shelf life: 36 months Active ingredient: Haloperidol (Haloperidol) Route of administration: Oral Vacation order: Prescription Release form: Prescription Storage conditions: In a dry place, In a dark place, Keep out of reach of children Maximum storage temperature, ° С: 25 Pharmacological group: N05AD01 Haloperidol Minimum age: 3 years

Active ingredients

Haloperidol

Release form

Pills

Composition

Haloperidol 1.5 mg

Pharmacological effect

Antipsychotic (neuroleptic), butyrophenone derivative. It has a pronounced antipsychotic effect due to blockade of depolarization or a decrease in the degree of excitation of dopamine neurons (reduced release) and blockade of postsynaptic dopamine D2 receptors in mesolimbic and mesocortical structures of the brain. It has a moderate sedative effect due to the blockade of the reticular formation of the brain stem. pronounced antiemetic effect due to blockade of dopamine D2 receptors in the trigger zone of the emetic center. hypothermic action and galactorrhea due to blockade of the hypothalamic dopamine receptors. Long-term use is accompanied by a change in the endocrine status, in the anterior lobe of the pituitary gland, prolactin production increases and gonadotropic hormone production decreases. The blockade of dopamine receptors in the dopamine pathways of the black-striped substance contributes to the development of extrapyramidal motor reactions. blockade of dopamine receptors in the tuberoinfundibular system causes a decrease in GH release. Virtually no anticholinergic action. Eliminates persistent changes in personality, delusions, hallucinations, mania, increases interest in the environment. Effective in patients resistant to other neuroleptics.It has some activating effect. In hyperactive children eliminates excessive motor activity, behavioral disorders (impulsivity, difficulty concentrating, aggressiveness). Unlike haloperidol, haloperidol decanoate is characterized by prolonged action.

Indications

Contraindications

Use during pregnancy and lactation

When ingested for adults, the initial dose is 0.5-5 mg 2-3 times / day, for elderly patients 0.5-2 mg 2-3 times / day. Further, depending on the patient's response to treatment, the dose is gradually increased in most cases to 5-10 mg / day. High doses (more than 40 mg / day) are used in rare cases, for a short time and in the absence of concomitant diseases. For children - 25-75 mg / kg / day in 2-3 doses. With the / m injection for adults, the initial single dose is 1-10 mg, the interval between repeated injections is 1-8 hours. when using the depot form, the dose is 50-300 mg 1 time in 4 weeks.For iv administration, a single dose of 0.5–50 mg, the frequency of administration and the dose for repeated administration depend on the indications and the clinical situation. Maximum doses: for oral administration for adults - 100 mg / day. V / m - 100 mg / day, with the use of the depot form - 300 mg / month.

Side effects

On the part of the central nervous system: headache, insomnia, anxiety, anxiety and fear, euphoria, agitation, drowsiness (especially at the beginning of treatment), akathisia, depression or euphoria, lethargy, epilepsy attack, development of a paradoxical reaction (exacerbation of psychosis, hallucinations). with long-term treatment, extrapyramidal disorders (including tardive dyskinesia, late dystonia, and anesthesia of the nervous system). Since the cardiovascular system: when used in high doses - arterial hypotension, tachycardia, arrhythmia, ECG changes (increased QT interval, signs of ventricular flutter and fibrillation). On the part of the digestive system: when used in high doses - loss of appetite, dry mouth, hypo-salivation, nausea, vomiting, constipation or diarrhea, abnormal liver function, including the development of jaundice. On the part of the blood system: rarely - light and temporary leukopenia, leukocytosis, agranulocytosis, slight erythropenia and a tendency to monocytosis. On the part of the endocrine system: gynecomastia, pain in the mammary glands, hyperprolactinemia, menstrual disorders, reduced potency, increased libido, priapism. Metabolism: hyper- and hypoglycemia, hyponatremia. increased sweating, peripheral edema, weight gain. On the part of the organ of vision: visual impairment, cataract, retinopathy, accommodation disturbances. Allergic reactions: rarely - skin rash, bronchospasm, laryngism, hyperpyrexia. Dermatological reactions: maculo-papular and acne-like skin changes. rarely - photosensitivity, alopecia. Effects due to cholinergic effects: dry mouth, hypo-salivation, urinary retention, constipation.

special instructions

On the part of the central nervous system: headache, insomnia, anxiety, anxiety and fear, euphoria, agitation, drowsiness (especially at the beginning of treatment), akathisia, depression or euphoria, lethargy, epilepsy attack, development of a paradoxical reaction (exacerbation of psychosis, hallucinations). with long-term treatment - extrapyramidal disorders (includingtardive dyskinesia, tardive dystonia and ZNS). Since the cardiovascular system: when used in high doses - arterial hypotension, tachycardia, arrhythmia, ECG changes (increased QT interval, signs of ventricular flutter and fibrillation). On the part of the digestive system: when used in high doses - loss of appetite, dry mouth, hypo-salivation, nausea, vomiting, constipation or diarrhea, abnormal liver function, including the development of jaundice. On the part of the blood system: rarely - light and temporary leukopenia, leukocytosis, agranulocytosis, slight erythropenia and a tendency to monocytosis. On the part of the endocrine system: gynecomastia, pain in the mammary glands, hyperprolactinemia, menstrual disorders, reduced potency, increased libido, priapism. Metabolism: hyper- and hypoglycemia, hyponatremia. increased sweating, peripheral edema, weight gain. On the part of the organ of vision: visual impairment, cataract, retinopathy, accommodation disturbances. Allergic reactions: rarely - skin rash, bronchospasm, laryngism, hyperpyrexia. Dermatological reactions: maculo-papular and acne-like skin changes. rarely - photosensitivity, alopecia. Effects due to cholinergic effects: dry mouth, hypo-salivation, urinary retention, constipation.

Prescription

Reviews