Basiron AC AS gel 2.5% 40 g
Condition: New product
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Active ingredients
Benzoyl peroxide
Release form
Gel
Composition
1 g of gel contains: Active substances: Adapalen - 0.001 g; Benzoyl peroxide - 0.025 g; Auxiliary substances: simulgel 600 PHA (copolymer of acrylamide and acryloyl dimethyl taurate 35-40%, isohexadecane 20-25%, polysorbate 80 5-10% sorbitan oleate 2.5%, water up to 100%) - 0.04 g, sodium dusate - 0.0005 g, disodium edetate - 0.001 g, glycerol-0.04 g, poloxamer 124 - 0.002 g, propylene glycol - 0.04 g , purified water - up to 1 g.
Pharmacological effect
Benzoyl peroxide exhibits antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis. It has a keratolytic effect, improves the oxygenation of tissues, suppresses sebum production in the sebaceous glands.
Pharmacokinetics
Benzoyl peroxide penetration through the skin is low. The main part of benzoyl peroxide is converted into benzoic acid, which, after absorption, enters the systemic circulation and is rapidly excreted by the kidneys. There is no cumulation in the tissues. Cutaneous application of Basiron AC AU in therapeutic doses does not lead to side effects of systemic action.
Indications
Acne.
Contraindications
Hypersensitivity to one of the incoming ingredients of the drug. Children under 12 years old.
Use during pregnancy and lactation
Pregnancy; Clinical experience with external use of benzoyl peroxide during pregnancy is absent or limited. Data on its effects on reproductive function, fertility, or peri- and postnatal development, as well as the properties of the teratogenicity and embryotoxicity of the drug when used in animals is also absent. With large-scale clinical use for the treatment of acne in mass concentrations up to 10% for several decades, benzoyl peroxide did not cause any effect on these indicators in the human body. Benzoyl peroxide should be used in pregnant women only if there is a clear indication after consulting a doctor. ; Breastfeeding period; It is not known whether benzoyl peroxide or its metabolites is excreted in human breast milk. The risk for newborns / infants cannot be excluded. In order to avoid contact of the infant with the drug during the breastfeeding period, application of Basiron AC AU gel on the chest area should be avoided.
Dosage and administration
Outwardly. With a light touch, apply the gel evenly on the affected surface once or twice a day (morning and evening) on clean, dry skin. The therapeutic effect develops after 4 weeks of treatment, a lasting improvement after 3 months of treatment. ; Repeated treatment is possible after consultation with the doctor.
Side effects
All adverse reactions identified during clinical trials are associated with skin disorders. With a decrease in the frequency of use of the drug or cancellation of treatment, they are reversible. The following categories are used to determine the frequency of occurrence of undesirable effects: Very often (≥1 / 10); Often (≥1 / 100 to <1/10); Infrequently (≥1 / 1 000 to <1/100); Rarely (≥1 / 10 000 to <1/1 000); Very rarely (<1/10 000); Disorders of the skin and subcutaneous tissues; Very often (≥1 / 10) Dry skin Erythema Skin peeling (desquamation) Sensation of burning skin; Often (≥1 / 100 to <1/10) Itching Skin soreness (pain, tingling), Skin irritation (contact dermatitis); Infrequently (≥1 / 1000 to <1/100) Allergic contact dermatitis; Unknown Swelling of the face; If any of the indicated in the instructions for side effects are aggravated or any other side effects not mentioned in are noted; instructions should be reported to the doctor immediately.
Overdose
Benzoyl Peroxide Gel is a drug shown for external use only. Excessive application of the drug will not lead to a more rapid achievement of the result or obtain a more pronounced effect, however, this may develop severe irritation. In this case, treatment with the drug should be discontinued and appropriate symptomatic therapy should be prescribed.
special instructions
The first use of the drug may cause a slight burning sensation, and within a few days - redness and peeling of the skin. Most patients in the first weeks of treatment appear noticeable peeling of the skin. It is not dangerous and, as a rule, passes within one or two days at a temporary termination of treatment. If severe irritation of the skin occurs, the frequency of application should be reduced, the drug should be temporarily or completely discontinued. When applying the gel, avoid contact with the mucous membranes of the eyes, mouth and nose.In case of accidental contact with the drug on the mucous membranes, it is necessary to thoroughly wash them with warm water. Care should be taken when applying the drug to the neck and other sensitive areas. The simultaneous use of products with peeling, drying or irritating effects (for example; alcohol containing products) is not recommended. ; Excessive exposure to sunlight and UV radiation, which are an additional cause of skin irritation, should be avoided. ; Due to the risk of sensitization, benzoyl peroxide gel should not be applied to damaged skin. ; Contact with dyed materials, including hair and dyed fabrics, may cause discoloration or discoloration.